Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2

Por Garcia, Christina B, Shaffer, Christian M, Eid, Josiane E
Publicado em 2012

Maternal Coding Variants in Complement Receptor 1 and Spontaneous Idiopathic Preterm Birth

Por McElroy, Jude J., Gutman, Courtney E., Shaffer, Christian M., Busch, Tamara D., Puttonen, Hilkka, Teramo, Kari, Murray, Jeffrey C., Hallman, Mikko, Muglia, Louis J.
Publicado em 2013

Novel Rare Variants in Congenital Cardiac Arrhythmia Genes are Frequent in Drug-induced Torsades de Pointes

Por Ramirez, Andrea H., Shaffer, Christian M., Delaney, Jessica T., Sexton, David P., Levy, Shawn E., Rieder, Mark J., Nickerson, Deborah A., George, Alfred L., Roden, Dan M.
Publicado em 2012

Comparison of HLA allelic imputation programs

Por Karnes, Jason H., Shaffer, Christian M., Bastarache, Lisa, Gaudieri, Silvana, Glazer, Andrew M., Steiner, Heidi E., Mosley, Jonathan D., Mallal, Simon, Denny, Joshua C., Phillips, Elizabeth J., Roden, Dan M.
Publicado no PLoS One (2017)

Identifying genetically driven clinical phenotypes using linear mixed models

Por Mosley, Jonathan D., Witte, John S., Larkin, Emma K., Bastarache, Lisa, Shaffer, Christian M., Karnes, Jason H., Stein, C. Michael, Phillips, Elizabeth, Hebbring, Scott J., Brilliant, Murray H., Mayer, John, Ye, Zhan, Roden, Dan M., Denny, Joshua C.
Publicado no Nat Commun (2016)

A polymorphism in HLA-G modifies statin benefit in asthma

Por Naidoo, Devesh, Wu, Ann C, Brilliant, Murray H, Denny, Joshua, Ingram, Christie, Kitchner, Terrie E, Linneman, James G, McGeachie, Michael J, Roden, Dan M, Shaffer, Christian M, Shah, Anushi, Weeke, Peter, Weiss, Scott T, Xu, Hua, Medina, Marisa W
Publicado no Pharmacogenomics J (2014)

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

Por Karnes, Jason H, Cronin, Robert M, Rollin, Jerome, Teumer, Alexander, Pouplard, Claire, Shaffer, Christian M, Blanquicett, Carmelo, Bowton, Erica A, Cowan, James D, Mosley, Jonathan D, Van Driest, Sara L, Weeke, Peter E, Wells, Quinn S, Bakchoul, Tamam, Denny, Joshua C, Greinacher, Andreas, Gruel, Yves, Roden, Dan M
Publicado no Thromb Haemost (2014)

CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids

Por Dahlin, Amber, Denny, Joshua, Roden, Dan M., Brilliant, Murray H., Ingram, Christie, Kitchner, Terrie E., Linneman, James G., Shaffer, Christian M., Weeke, Peter, Xu, Hua, Kubo, Michiaki, Tamari, Mayumi, Clemmer, George L., Ziniti, John, McGeachie, Michael J., Tantisira, Kelan G., Weiss, Scott T., Wu, Ann Chen
Publicado no Immun Inflamm Dis (2015)

CTNNA3 and SEMA3D: promising loci for asthma exacerbation identified through multiple GWAS

Por McGeachie, Michael J., Wu, Ann C., Tse, Sze Man, Clemmer, George L., Sordillo, Joanne, Himes, Blanca E., Lasky-Su, Jessica, Chase, Robert P., Martinez, Fernando D., Weeke, Peter, Shaffer, Christian M., Xu, Hua, Denny, Josh C., Roden, Dan M., Panettieri, Reynold A., Raby, Benjamin A., Weiss, Scott T., Tantisira, Kelan G.
Publicado no J Allergy Clin Immunol (2015)

Kcnj11 Ablation is Associated with Increased Nitro-Oxidative Stress During Ischemia-Reperfusion Injury: Implications for Human Ischemic Cardiomyopathy

Por Zhang, Bo, Novitskaya, Tatiana, Wheeler, Debra G., Xu, Zhaobin, Chepurko, Elena, Huttinger, Ryan, He, Heng, Varadharaj, Saradhadevi, Zweier, Jay L., Song, Yanna, Xu, Meng, Harrell, Frank E., Su, Yan Ru, Absi, Tarek, Kohr, Mark J., Ziolo, Mark T., Roden, Dan M., Shaffer, Christian M., Galindo, Cristi L., Wells, Quinn S., Gumina, Richard J.
Publicado no Circ Heart Fail (2017)

Azithromycin Causes a Novel Proarrhythmic Syndrome

Por Yang, Zhenjiang, Prinsen, Joseph K., Bersell, Kevin R., Shen, Wangzhen, Yermalitskaya, Liudmila, Sidorova, Tatiana, Luis, Paula B., Hall, Lynn, Zhang, Wei, Du, Liping, Milne, Ginger, Tucker, Patrick, George, Alfred L., Campbell, Courtney M., Pickett, Robert A., Shaffer, Christian M., Chopra, Nagesh, Yang, Tao, Knollmann, Bjorn C., Roden, Dan M., Murray, Katherine T.
Publicado no Circ Arrhythm Electrophysiol (2017)

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile using Historical Data

Por Mosley, Jonathan D., Van Driest, Sara L., Wells, Quinn S., Shaffer, Christian M., Edwards, Todd L., Bastarache, Lisa, McCarty, Catherine A., Thompson, Will, Chute, Christopher G., Jarvik, Gail P., Crosslin, David R., Larson, Eric B., Kullo, Iftikhar J., Pacheco, Jennifer A., Peissig, Peggy L., Brilliant, Murray H., Linneman, James G., Denny, Josh C., Roden, Dan M.
Publicado no Circ Cardiovasc Genet (2016)

CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease

Por Hoh, Brian L., Gong, Yan, McDonough, Caitrin W., Waters, Michael F., Royster, Adrienne J., Sheehan, Tiffany O., Burkley, Ben, Langaee, Taimour Y., Mocco, J, Zuckerman, Scott L., Mummareddy, Nishit, Stephens, Marcus L., Ingram, Christie, Shaffer, Christian M., Denny, Joshua C., Brilliant, Murray H., Kitchner, Terrie E., Linneman, James G., Roden, Dan M., Johnson, Julie A.
Publicado no J Neurosurg (2015)

Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy

Por Van Driest, Sara L., McGregor, Tracy L., Velez Edwards, Digna R., Saville, Ben R., Kitchner, Terrie E., Hebbring, Scott J., Brilliant, Murray, Jouni, Hayan, Kullo, Iftikhar J., Creech, C. Buddy, Kannankeril, Prince J., Vear, Susan I., Brothers, Kyle B., Bowton, Erica A., Shaffer, Christian M., Patel, Neelam, Delaney, Jessica T., Bradford, Yuki, Wilson, Sarah, Olson, Lana M., Crawford, Dana C., Potts, Amy L., Ho, Richard H., Roden, Dan M., Denny, Josh C.
Publicado no PLoS One (2015)

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

Por Cronin, Robert M., Field, Julie R., Bradford, Yuki, Shaffer, Christian M., Carroll, Robert J., Mosley, Jonathan D., Bastarache, Lisa, Edwards, Todd L., Hebbring, Scott J., Lin, Simon, Hindorff, Lucia A., Crane, Paul K., Pendergrass, Sarah A., Ritchie, Marylyn D., Crawford, Dana C., Pathak, Jyotishman, Bielinski, Suzette J., Carrell, David S., Crosslin, David R., Ledbetter, David H., Carey, David J., Tromp, Gerard, Williams, Marc S., Larson, Eric B., Jarvik, Gail P., Peissig, Peggy L., Brilliant, Murray H., McCarty, Catherine A., Chute, Christopher G., Kullo, Iftikhar J., Bottinger, Erwin, Chisholm, Rex, Smith, Maureen E., Roden, Dan M., Denny, Joshua C.
Publicado em 2014

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-wide Association Studies

Por Joshi, Amit D., Andersson, Charlotte, Buch, Stephan, Stender, Stefan, Noordam, Raymond, Weng, Lu-Chen, Weeke, Peter E., Auer, Paul L., Boehm, Bernhard, Chen, Constance, Choi, Hyon, Curhan, Gary, Denny, Joshua C., De Vivo, Immaculata, Eicher, John D., Ellinghaus, David, Folsom, Aaron R., Fuchs, Charles, Gala, Manish, Haessler, Jeffrey, Hofman, Albert, Hu, Frank, Hunter, David J., Janssen, Harry L.A., Kang, Jae H., Kooperberg, Charles, Kraft, Peter, Kratzer, Wolfgang, Lieb, Wolfgang, Lutsey, Pamela L., Murad, Sarwa Darwish, Nordestgaard, Børge G., Pasquale, Louis R., Reiner, Alex P., Ridker, Paul M, Rimm, Eric, Rose, Lynda M., Shaffer, Christian M., Schafmayer, Clemens, Tamimi, Rulla M., Uitterlinden, André G, Völker, Uwe, Völzke, Henry, Wakabayashi, Yoshiyuki, Wiggs, Janey L., Zhu, Jun, Roden, Dan M., Stricker, Bruno H., Tang, Weihong, Teumer, Alexander, Hampe, Jochen, Tybjærg-Hansen, Anne, Chasman, Daniel I., Chan, Andrew T., Johnson, Andrew D.
Publicado no Gastroenterology (2016)

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

Por Teumer, Alexander, Tin, Adrienne, Sorice, Rossella, Gorski, Mathias, Yeo, Nan Cher, Chu, Audrey Y., Li, Man, Li, Yong, Mijatovic, Vladan, Ko, Yi-An, Taliun, Daniel, Luciani, Alessandro, Chen, Ming-Huei, Yang, Qiong, Foster, Meredith C., Olden, Matthias, Hiraki, Linda T., Tayo, Bamidele O., Fuchsberger, Christian, Dieffenbach, Aida Karina, Shuldiner, Alan R., Smith, Albert V., Zappa, Allison M., Lupo, Antonio, Kollerits, Barbara, Ponte, Belen, Stengel, Bénédicte, Krämer, Bernhard K., Paulweber, Bernhard, Mitchell, Braxton D., Hayward, Caroline, Helmer, Catherine, Meisinger, Christa, Gieger, Christian, Shaffer, Christian M., Müller, Christian, Langenberg, Claudia, Ackermann, Daniel, Siscovick, David, Boerwinkle, Eric, Kronenberg, Florian, Ehret, Georg B., Homuth, Georg, Waeber, Gerard, Navis, Gerjan, Gambaro, Giovanni, Malerba, Giovanni, Eiriksdottir, Gudny, Li, Guo, Wichmann, H. Erich, Grallert, Harald, Wallaschofski, Henri, Völzke, Henry, Brenner, Herrmann, Kramer, Holly, Leach, I. Mateo, Rudan, Igor, Hillege, Hans L., Beckmann, Jacques S., Lambert, Jean Charles, Luan, Jian'an, Zhao, Jing Hua, Chalmers, John, Coresh, Josef, Denny, Joshua C., Butterbach, Katja, Launer, Lenore J., Ferrucci, Luigi, Kedenko, Lyudmyla, Haun, Margot, Metzger, Marie, Woodward, Mark, Hoffman, Matthew J., Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Wareham, Nicholas J., Endlich, Nicole, Soranzo, Nicole, Polasek, Ozren, van der Harst, Pim, Pramstaller, Peter Paul, Vollenweider, Peter, Wild, Philipp S., Gansevoort, Ron T., Rettig, Rainer, Biffar, Reiner, Carroll, Robert J., Katz, Ronit, Loos, Ruth J.F., Hwang, Shih-Jen, Coassin, Stefan, Bergmann, Sven, Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Corre, Tanguy, Zeller, Tanja, Illig, Thomas, Aspelund, Thor, Tanaka, Toshiko, Lendeckel, Uwe, Völker, Uwe, Gudnason, Vilmundur, Chouraki, Vincent, Koenig, Wolfgang, Kutalik, Zoltan, O'Connell, Jeffrey R., Parsa, Afshin, Heid, Iris M., Paterson, Andrew D., de Boer, Ian H., Devuyst, Olivier, Lazar, Jozef, Endlich, Karlhans, Susztak, Katalin, Tremblay, Johanne, Hamet, Pavel, Jacob, Howard J., Böger, Carsten A., Fox, Caroline S., Pattaro, Cristian, Köttgen, Anna
Publicado no Diabetes (2016)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Por Pattaro, Cristian, Teumer, Alexander, Gorski, Mathias, Chu, Audrey Y., Li, Man, Mijatovic, Vladan, Garnaas, Maija, Tin, Adrienne, Sorice, Rossella, Li, Yong, Taliun, Daniel, Olden, Matthias, Foster, Meredith, Yang, Qiong, Chen, Ming-Huei, Pers, Tune H., Johnson, Andrew D., Ko, Yi-An, Fuchsberger, Christian, Tayo, Bamidele, Nalls, Michael, Feitosa, Mary F., Isaacs, Aaron, Dehghan, Abbas, d'Adamo, Pio, Adeyemo, Adebowale, Dieffenbach, Aida Karina, Zonderman, Alan B., Nolte, Ilja M., van der Most, Peter J., Wright, Alan F., Shuldiner, Alan R., Morrison, Alanna C., Hofman, Albert, Smith, Albert V., Dreisbach, Albert W., Franke, Andre, Uitterlinden, Andre G., Metspalu, Andres, Tonjes, Anke, Lupo, Antonio, Robino, Antonietta, Johansson, Åsa, Demirkan, Ayse, Kollerits, Barbara, Freedman, Barry I., Ponte, Belen, Oostra, Ben A., Paulweber, Bernhard, Krämer, Bernhard K., Mitchell, Braxton D., Buckley, Brendan M., Peralta, Carmen A., Hayward, Caroline, Helmer, Catherine, Rotimi, Charles N., Shaffer, Christian M., Müller, Christian, Sala, Cinzia, van Duijn, Cornelia M., Saint-Pierre, Aude, Ackermann, Daniel, Shriner, Daniel, Ruggiero, Daniela, Toniolo, Daniela, Lu, Yingchang, Cusi, Daniele, Czamara, Darina, Ellinghaus, David, Siscovick, David S., Ruderfer, Douglas, Gieger, Christian, Grallert, Harald, Rochtchina, Elena, Atkinson, Elizabeth J., Holliday, Elizabeth G., Boerwinkle, Eric, Salvi, Erika, Bottinger, Erwin P., Murgia, Federico, Rivadeneira, Fernando, Ernst, Florian, Kronenberg, Florian, Hu, Frank B., Navis, Gerjan J., Curhan, Gary C., Ehret, George B., Homuth, Georg, Coassin, Stefan, Thun, Gian-Andri, Pistis, Giorgio, Gambaro, Giovanni, Malerba, Giovanni, Montgomery, Grant W., Eiriksdottir, Gudny, Jacobs, Gunnar, Li, Guo, Wichmann, H-Erich, Campbell, Harry, Schmidt, Helena, Wallaschofski, Henri, Völzke, Henry, Brenner, Hermann, Kroemer, Heyo K., Kramer, Holly, Lin, Honghuang, Leach, I. Mateo, Ford, Ian, Guessous, Idris, Rudan, Igor, Prokopenko, Inga, Borecki, Ingrid, Heid, Iris M., Kolcic, Ivana, Persico, Ivana, Jukema, J. Wouter, Wilson, James F., Felix, Janine F., Divers, Jasmin, Lambert, Jean-Charles, Stafford, Jeanette M., Gaspoz, Jean-Michel, Smith, Jennifer A., Faul, Jessica D., Wang, Jie Jin, Ding, Jingzhong, Hirschhorn, Joel N., Attia, John, Whitfield, John B., Chalmers, John, Viikari, Jorma, Coresh, Josef, Denny, Joshua C., Karjalainen, Juha, Fernandes, Jyotika K., Endlich, Karlhans, Butterbach, Katja, Keene, Keith L., Lohman, Kurt, Portas, Laura, Launer, Lenore J., Lyytikäinen, Leo-Pekka, Yengo, Loic, Franke, Lude, Ferrucci, Luigi, Rose, Lynda M., Kedenko, Lyudmyla, Rao, Madhumathi, Struchalin, Maksim, Kleber, Marcus E., Cavalieri, Margherita, Haun, Margot, Cornelis, Marilyn C., Ciullo, Marina, Pirastu, Mario, de Andrade, Mariza, McEvoy, Mark A., Woodward, Mark, Adam, Martin, Cocca, Massimiliano, Nauck, Matthias, Imboden, Medea, Waldenberger, Melanie, Pruijm, Menno, Metzger, Marie, Stumvoll, Michael, Evans, Michele K., Sale, Michele M., Kähönen, Mika, Boban, Mladen, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Bouatia-Naji, Nabila, Martin, Nicholas G., Hastie, Nick, Probst-Hensch, Nicole, Soranzo, Nicole, Devuyst, Olivier, Raitakari, Olli, Gottesman, Omri, Franco, Oscar H., Polasek, Ozren, Gasparini, Paolo, Munroe, Patricia B., Ridker, Paul M., Mitchell, Paul, Muntner, Paul, Meisinger, Christa, Smit, Johannes H., Kovacs, Peter, Wild, Philipp S., Froguel, Philippe, Rettig, Rainer, Mägi, Reedik, Biffar, Reiner, Schmidt, Reinhold, Middelberg, Rita P. S., Carroll, Robert J., Penninx, Brenda W., Scott, Rodney J., Katz, Ronit, Sedaghat, Sanaz, Wild, Sarah H., Kardia, Sharon L. R., Ulivi, Sheila, Hwang, Shih-Jen, Enroth, Stefan, Kloiber, Stefan, Trompet, Stella, Stengel, Benedicte, Hancock, Stephen J., Turner, Stephen T., Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Zeller, Tanja, Zemunik, Tatijana, Lehtimäki, Terho, Illig, Thomas, Aspelund, Thor, Nikopensius, Tiit, Esko, Tonu, Tanaka, Toshiko, Gyllensten, Ulf, Völker, Uwe, Emilsson, Valur, Vitart, Veronique, Aalto, Ville, Gudnason, Vilmundur, Chouraki, Vincent, Chen, Wei-Min, Igl, Wilmar, März, Winfried, Koenig, Wolfgang, Lieb, Wolfgang, Loos, Ruth J. F., Liu, Yongmei, Snieder, Harold, Pramstaller, Peter P., Parsa, Afshin, O'Connell, Jeffrey R., Susztak, Katalin, Hamet, Pavel, Tremblay, Johanne, de Boer, Ian H., Böger, Carsten A., Goessling, Wolfram, Chasman, Daniel I., Köttgen, Anna, Kao, W. H. Linda, Fox, Caroline S.
Publicado no Nat Commun (2016)