Novel Rare Variants in Congenital Cardiac Arrhythmia Genes are Frequent in Drug-induced Torsades de Pointes

Marked prolongation of the QT interval and polymorphic ventricular tachycardia following medication (drug-induced long QT syndrome, diLQTS) is a severe adverse drug reaction (ADR) that phenocopies congenital long QT syndrome (cLQTS) and one of the leading causes for drug withdrawal and relabeling. W...

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Detalhes bibliográficos
Main Authors: Ramirez, Andrea H., Shaffer, Christian M., Delaney, Jessica T., Sexton, David P., Levy, Shawn E., Rieder, Mark J., Nickerson, Deborah A., George, Alfred L., Roden, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422407/
https://ncbi.nlm.nih.gov/pubmed/22584458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2012.14
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