Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile using Historical Data

BACKGROUND: Continued reductions in morbidity and mortality attributable to ischemic heart disease (IHD) require an understanding of the changing epidemiology of this disease. We hypothesized that we could use genetic correlations, which quantitate the shared genetic architectures of phenotype pairs...

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Detalhes bibliográficos
Publicado no:Circ Cardiovasc Genet
Main Authors: Mosley, Jonathan D., Van Driest, Sara L., Wells, Quinn S., Shaffer, Christian M., Edwards, Todd L., Bastarache, Lisa, McCarty, Catherine A., Thompson, Will, Chute, Christopher G., Jarvik, Gail P., Crosslin, David R., Larson, Eric B., Kullo, Iftikhar J., Pacheco, Jennifer A., Peissig, Peggy L., Brilliant, Murray H., Linneman, James G., Denny, Josh C., Roden, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177499/
https://ncbi.nlm.nih.gov/pubmed/27780847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.116.001530
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