A Genome- and Phenome-Wide Association Study to Identify Genetic Variants Influencing Platelet Count and Volume and their Pleiotropic Effects

Platelets are enucleated cell fragments derived from megakaryocytes that play key roles in hemostasis and in the pathogenesis of atherothrombosis and cancer. Platelet traits are highly heritable and identification of genetic variants associated with platelet traits and assessing their pleiotropic ef...

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Main Authors: Shameer, Khader, Denny, Joshua C., Ding, Keyue, Jouni, Hayan, Crosslin, David R., de Andrade, Mariza, Chute, Christopher G., Peissig, Peggy, Pacheco, Jennifer A., Li, Rongling, Bastarache, Lisa, Kho, Abel N., Ritchie, Marylyn D, Masys, Daniel R., Chisholm, Rex L., Larson, Eric B., McCarty, Catherine A., Roden, Dan M., Jarvik, Gail P., Kullo, Iftikhar J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880605/
https://ncbi.nlm.nih.gov/pubmed/24026423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1355-7
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