Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality

af Brouwers, Martijn C. G. J., Simons, Nynke, Stehouwer, Coen D. A., Isaacs, Aaron
Udgivet i Diabetologia (2019)

Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease

af Brouwers, Martijn C.G.J., Simons, Nynke, Stehouwer, Coen D.A., Koek, Ger H., Schaper, Nicolaas C., Isaacs, Aaron
Udgivet i Hepatol Commun (2019)

Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval

af Silva, Claudia Tamar, Kors, Jan A., Amin, Najaf, Dehghan, Abbas, Witteman, Jacqueline C. M., Willemsen, Rob, Oostra, Ben A., van Duijn, Cornelia M., Isaacs, Aaron
Udgivet i Hum Genet (2015)

Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes

af Jainandunsing, Sjaam, Özcan, Behiye, Rietveld, Trinet, van Miert, Joram N. I., Isaacs, Aaron J., Langendonk, Janneke G., de Rooij, Felix W. M., Sijbrands, Eric J. G.
Udgivet i Acta Diabetol (2014)

A systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer risk

af Elands, Rachel J. J., Simons, Colinda C. J. M., Riemenschneider, Mona, Isaacs, Aaron, Schouten, Leo J., Verhage, Bas A., Van Steen, Kristel, Godschalk, Roger W. L., van den Brandt, Piet A., Stoll, Monika, Weijenberg, Matty P.
Udgivet i Sci Rep (2017)

Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: The Erasmus Rucphen Family Study

af Isaacs, Aaron, Sayed-Tabatabaei, Fakhredin A., Aulchenko, Yurii S., Zillikens, M. Carola, Sijbrands, Eric J. G., Schut, Anna F. C., Rutten, Wim P. F., Pols, Huibert A. P., Witteman, Jacqueline C. M., Oostra, Ben A., van Duijn, Cornelia M.
Udgivet 2007

A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study

af Silva, Claudia T., Zorkoltseva, Irina V., Amin, Najaf, Demirkan, Ayşe, van Leeuwen, Elisabeth M., Kors, Jan A., van den Berg, Marten, Stricker, Bruno H., Uitterlinden, André G., Kirichenko, Anatoly V., Witteman, Jacqueline C. M., Willemsen, Rob, Oostra, Ben A., Axenovich, Tatiana I., van Duijn, Cornelia M., Isaacs, Aaron
Udgivet i Front Genet (2016)

A genome-wide association scan of RR and QT interval duration in three European genetically isolated populations. The EUROSPAN project

af Marroni, Fabio, Pfeufer, Arne, Aulchenko, Yurii S, Franklin, Christopher S, Isaacs, Aaron, Pichler, Irene, Wild, Sarah H, Oostra, Ben A, Wright, Alan F, Campbell, Harry, Witteman, Jacqueline C, Kääb, Stefan, Hicks, Andrew A, Gyllensten, Ulf, Rudan, Igor, Meitinger, Thomas, Pattaro, Cristian, van Duijn, Cornelia M, Wilson, James F, Pramstaller, Peter P
Udgivet 2009

Association of the IGF1 gene with fasting insulin levels

af Willems, Sara M, Cornes, Belinda K, Brody, Jennifer A, Morrison, Alanna C, Lipovich, Leonard, Dauriz, Marco, Chen, Yuning, Liu, Ching-Ti, Rybin, Denis V, Gibbs, Richard A, Muzny, Donna, Pankow, James S, Psaty, Bruce M, Boerwinkle, Eric, Rotter, Jerome I, Siscovick, David S, Vasan, Ramachandran S, Kaplan, Robert C, Isaacs, Aaron, Dupuis, Josée, van Duijn, Cornelia M, Meigs, James B
Udgivet i Eur J Hum Genet (2016)

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

af Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Udgivet i J Autoimmun (2016)

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

af Silva, Claudia Tamar, Zorkoltseva, Irina V., Niemeijer, Maartje N., van den Berg, Marten E., Amin, Najaf, Demirkan, Ayşe, van Leeuwen, Elisa, Iglesias, Adriana I., Piñeros-Hernández, Laura B., Restrepo, Carlos M., Kors, Jan A., Kirichenko, Anatoly V., Willemsen, Rob, Oostra, Ben A., Stricker, Bruno H., Uitterlinden, André G., Axenovich, Tatiana I., van Duijn, Cornelia M., Isaacs, Aaron
Udgivet i BMC Med Genomics (2018)

A Genome-Wide Association Study of Optic Disc Parameters

af Ramdas, Wishal D., van Koolwijk, Leonieke M. E., Ikram, M. Kamran, Jansonius, Nomdo M., de Jong, Paulus T. V. M., Bergen, Arthur A. B., Isaacs, Aaron, Amin, Najaf, Aulchenko, Yurii S., Wolfs, Roger C. W., Hofman, Albert, Rivadeneira, Fernando, Oostra, Ben A., Uitterlinden, Andre G., Hysi, Pirro, Hammond, Christopher J., Lemij, Hans G., Vingerling, Johannes R., Klaver, Caroline C. W., van Duijn, Cornelia M.
Udgivet 2010

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level

af Pattaro, Cristian, De Grandi, Alessandro, Vitart, Veronique, Hayward, Caroline, Franke, Andre, Aulchenko, Yurii S, Johansson, Asa, Wild, Sarah H, Melville, Scott A, Isaacs, Aaron, Polasek, Ozren, Ellinghaus, David, Kolcic, Ivana, Nöthlings, Ute, Zgaga, Lina, Zemunik, Tatijana, Gnewuch, Carsten, Schreiber, Stefan, Campbell, Susan, Hastie, Nick, Boban, Mladen, Meitinger, Thomas, Oostra, Ben A, Riegler, Peter, Minelli, Cosetta, Wright, Alan F, Campbell, Harry, van Duijn, Cornelia M, Gyllensten, Ulf, Wilson, James F, Krawczak, Michael, Rudan, Igor, Pramstaller, Peter P
Udgivet 2010

Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

af Broer, Linda, Codd, Veryan, Nyholt, Dale R, Deelen, Joris, Mangino, Massimo, Willemsen, Gonneke, Albrecht, Eva, Amin, Najaf, Beekman, Marian, de Geus, Eco J C, Henders, Anjali, Nelson, Christopher P, Steves, Claire J, Wright, Margie J, de Craen, Anton J M, Isaacs, Aaron, Matthews, Mary, Moayyeri, Alireza, Montgomery, Grant W, Oostra, Ben A, Vink, Jacqueline M, Spector, Tim D, Slagboom, P Eline, Martin, Nicholas G, Samani, Nilesh J, van Duijn, Cornelia M, Boomsma, Dorret I
Udgivet 2013

The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels

af van Leeuwen, Elisabeth M., Smouter, Françoise A. S., Kam-Thong, Tony, Karbalai, Nazanin, Smith, Albert V., Harris, Tamara B., Launer, Lenore J., Sitlani, Colleen M., Li, Guo, Brody, Jennifer A., Bis, Joshua C., White, Charles C., Jaiswal, Alok, Oostra, Ben A., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., Boerwinkle, Eric, Ballantyne, Christie M., Gudnason, Vilmundur, Psaty, Bruce M., Cupples, L. Adrienne, Järvelin, Marjo-Riitta, Ripatti, Samuli, Isaacs, Aaron, Müller-Myhsok, Bertram, Karssen, Lennart C., van Duijn, Cornelia M.
Udgivet 2014

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

af Johansson, Åsa, Marroni, Fabio, Hayward, Caroline, Franklin, Christopher S., Kirichenko, Anatoly V., Jonasson, Inger, Hicks, Andrew A., Vitart, Veronique, Isaacs, Aaron, Axenovich, Tatiana, Campbell, Susan, Dunlop, Malcolm G., Floyd, Jamie, Hastie, Nick, Hofman, Albert, Knott, Sara, Kolcic, Ivana, Pichler, Irene, Polasek, Ozren, Rivadeneira, Fernando, Tenesa, Albert, Uitterlinden, André G., Wild, Sarah H., Zorkoltseva, Irina V., Meitinger, Thomas, Wilson, James F., Rudan, Igor, Campbell, Harry, Pattaro, Cristian, Pramstaller, Peter, Oostra, Ben A., Wright, Alan F., van Duijn, Cornelia M., Aulchenko, Yurii S., Gyllensten, Ulf
Udgivet 2009

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

af Verweij, Niek, Mateo Leach, Irene, Isaacs, Aaron, Arking, Dan E., Bis, Joshua C., Pers, Tune H., Van Den Berg, Marten E., Lyytikäinen, Leo-Pekka, Barnett, Phil, Wang, Xinchen, Soliman, Elsayed Z., Van Duijn, Cornelia M., Kähönen, Mika, Van Veldhuisen, Dirk J., Kors, Jan A., Raitakari, Olli T., Silva, Claudia T., Lehtimäki, Terho, Hillege, Hans L., Hirschhorn, Joel N., Boyer, Laurie A., Van Gilst, Wiek H., Alonso, Alvaro, Sotoodehnia, Nona, Eijgelsheim, Mark, De Boer, Rudolf A., De Bakker, Paul I. W., Franke, Lude, Van Der Harst, Pim
Udgivet i Hum Mol Genet (2016)

Nucleotide Excision DNA Repair is Associated with Age-Related Vascular Dysfunction

af Durik, Matej, Kavousi, Maryam, van der Pluijm, Ingrid, Isaacs, Aaron, Cheng, Caroline, Verdonk, Koen, Loot, Annemarieke E., Oeseburg, Hisko, Musterd-Bhaggoe, Usha, Leijten, Frank, van Veghel, Richard, de Vries, Rene, Rudez, Goran, Brandt, Renata, Ridwan, Yanto R., van Deel, Elza D., de Boer, Martine, Tempel, Dennie, Fleming, Ingrid, Mitchell, Gary F., Verwoert, Germaine C., Tarasov, Kirill V., Uitterlinden, Andre G., Hofman, Albert, Duckers, Henricus J., van Duijn, Cornelia M., Oostra, Ben A., Witteman, Jacqueline C.M., Duncker, Dirk J., Danser, A.H. Jan, Hoeijmakers, Jan H., Roks, Anton J.M.
Udgivet 2012

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

af Amin, Najaf, Hottenga, Jouke-Jan, Hansell, Narelle K, Janssens, A Cecile JW, de Moor, Marleen HM, Madden, Pamela AF, Zorkoltseva, Irina V, Penninx, Brenda W, Terracciano, Antonio, Uda, Manuela, Tanaka, Toshiko, Esko, Tonu, Realo, Anu, Ferrucci, Luigi, Luciano, Michelle, Davies, Gail, Metspalu, Andres, Abecasis, Goncalo R, Deary, Ian J, Raikkonen, Katri, Bierut, Laura J, Costa, Paul T, Saviouk, Viatcheslav, Zhu, Gu, Kirichenko, Anatoly V, Isaacs, Aaron, Aulchenko, Yurii S, Willemsen, Gonneke, Heath, Andrew C, Pergadia, Michele L, Medland, Sarah E, Axenovich, Tatiana I, de Geus, Eco, Montgomery, Grant W, Wright, Margaret J, Oostra, Ben A, Martin, Nicholas G, Boomsma, Dorret I, van Duijn, Cornelia M
Udgivet 2013

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

af Hicks, Andrew A., Pramstaller, Peter P., Johansson, Åsa, Vitart, Veronique, Rudan, Igor, Ugocsai, Peter, Aulchenko, Yurii, Franklin, Christopher S., Liebisch, Gerhard, Erdmann, Jeanette, Jonasson, Inger, Zorkoltseva, Irina V., Pattaro, Cristian, Hayward, Caroline, Isaacs, Aaron, Hengstenberg, Christian, Campbell, Susan, Gnewuch, Carsten, Janssens, A. CecileJ.W., Kirichenko, Anatoly V., König, Inke R., Marroni, Fabio, Polasek, Ozren, Demirkan, Ayse, Kolcic, Ivana, Schwienbacher, Christine, Igl, Wilmar, Biloglav, Zrinka, Witteman, Jacqueline C. M., Pichler, Irene, Zaboli, Ghazal, Axenovich, Tatiana I., Peters, Annette, Schreiber, Stefan, Wichmann, H.-Erich, Schunkert, Heribert, Hastie, Nick, Oostra, Ben A., Wild, Sarah H., Meitinger, Thomas, Gyllensten, Ulf, van Duijn, Cornelia M., Wilson, James F., Wright, Alan, Schmitz, Gerd, Campbell, Harry
Udgivet 2009