From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

著者: Kumar, Vinod, Wijmenga, Cisca, Withoff, Sebo
出版事項 2012

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

著者: Moerkens, Renée, Mooiweer, Joram, Withoff, Sebo, Wijmenga, Cisca
出版年 United European Gastroenterol J (2019)

Small and Long Regulatory RNAs in the Immune System and Immune Diseases

著者: Stachurska, Anna, Zorro, Maria M., van der Sijde, Marijke R., Withoff, Sebo
出版事項 2014

Intestinal Barrier Function in Gluten-Related Disorders

著者: Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Withoff, Sebo, Branchi, Federica, Schumann, Michael
出版年 Nutrients (2019)

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge

著者: Bondar, Constanza, Plaza-Izurieta, Leticia, Fernandez-Jimenez, Nora, Irastorza, Iñaki, Withoff, Sebo, Wijmenga, Cisca, Chirdo, Fernando, Bilbao, Jose Ramon
出版事項 2014

Molecular Biomarkers for Celiac Disease: Past, Present and Future

著者: Ramírez-Sánchez, Aarón D., Tan, Ineke L., Gonera-de Jong, B.C., Visschedijk, Marijn C., Jonkers, Iris, Withoff, Sebo
出版年 Int J Mol Sci (2020)

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

著者: Spierings, Diana C., McGoldrick, Daniel, Hamilton-Easton, Ann Marie, Neale, Geoffrey, Murchison, Elizabeth P., Hannon, Greg J., Green, Douglas R., Withoff, Sebo
出版事項 2011

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

著者: Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
出版年 Front Immunol (2019)

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

著者: Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
出版年 J Autoimmun (2020)

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity

著者: Hrdlickova, Barbara, Kumar, Vinod, Kanduri, Kartiek, Zhernakova, Daria V, Tripathi, Subhash, Karjalainen, Juha, Lund, Riikka J, Li, Yang, Ullah, Ubaid, Modderman, Rutger, Abdulahad, Wayel, Lähdesmäki, Harri, Franke, Lude, Lahesmaa, Riitta, Wijmenga, Cisca, Withoff, Sebo
出版年 Genome Med (2014)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

著者: Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
出版事項 2013

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

著者: Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
出版年 PLoS One (2017)

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

著者: Jaeger, Martin, Matzaraki, Vasiliki, Aguirre-Gamboa, Raúl, Gresnigt, Mark S, Chu, Xiaojing, Johnson, Melissa D, Oosting, Marije, Smeekens, Sanne P, Withoff, Sebo, Jonkers, Iris, Perfect, John R, van de Veerdonk, Frank L, Kullberg, Bart-Jan, Joosten, Leo A B, Li, Yang, Wijmenga, Cisca, Netea, Mihai G, Kumar, Vinod
出版年 J Infect Dis (2019)

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

著者: Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
出版年 Nat Immunol (2018)

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

著者: van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
出版年 Front Genet (2021)

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

著者: Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
出版年 Sci Rep (2021)

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

著者: Almeida, Rodrigo, Ricaño-Ponce, Isis, Kumar, Vinod, Deelen, Patrick, Szperl, Agata, Trynka, Gosia, Gutierrez-Achury, Javier, Kanterakis, Alexandros, Westra, Harm-Jan, Franke, Lude, Swertz, Morris A., Platteel, Mathieu, Bilbao, Jose Ramon, Barisani, Donatella, Greco, Luigi, Mearin, Luisa, Wolters, Victorien M., Mulder, Chris, Mazzilli, Maria Cristina, Sood, Ajit, Cukrowska, Bozena, Núñez, Concepción, Pratesi, Riccardo, Withoff, Sebo, Wijmenga, Cisca
出版事項 2014

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidemia

著者: Kumar, Vinod, Cheng, Shih-Chin, Johnson, Melissa D., Smeekens, Sanne P., Wojtowicz, Agnieszka, Giamarellos-Bourboulis, Evangelos, Karjalainen, Juha, Franke, Lude, Withoff, Sebo, Plantinga, Theo S., van de Veerdonk, Frank L., van der Meer, Jos W.M., Joosten, Leo A.B., Bochud, Pierre-Yves, Marchetti, Oscar, Perfect, John R., Xavier, Ramnik, Kullberg, Bart Jan, Wijmenga, Cisca, Netea, Mihai G.
出版年 Nat Commun (2014)

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

著者: Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
出版年 J Autoimmun (2016)

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease

著者: Hrdlickova, Barbara, Mulder, Chris J., Malamut, Georgia, Meresse, Bertrand, Platteel, Mathieu, Kamatani, Yoichiro, Ricaño-Ponce, Isis, van Wanrooij, Roy L.J., Zorro, Maria M., Bonder, Marc Jan, Gutierrez-Achury, Javier, Cellier, Christophe, Zhernakova, Alexandra, Nijeboer, Petula, Galan, Pilar, Withoff, Sebo, Lathrop, Mark, Bouma, Gerd, Xavier, Ramnik J., Jabri, Bana, Bensussan, Nadine C., Wijmenga, Cisca, Kumar, Vinod
出版年 Eur J Gastroenterol Hepatol (2018)