From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

بواسطة Kumar, Vinod, Wijmenga, Cisca, Withoff, Sebo
منشور في 2012

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

بواسطة Moerkens, Renée, Mooiweer, Joram, Withoff, Sebo, Wijmenga, Cisca
الحاوية / القاعدة United European Gastroenterol J (2019)

Small and Long Regulatory RNAs in the Immune System and Immune Diseases

بواسطة Stachurska, Anna, Zorro, Maria M., van der Sijde, Marijke R., Withoff, Sebo
منشور في 2014

Intestinal Barrier Function in Gluten-Related Disorders

بواسطة Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Withoff, Sebo, Branchi, Federica, Schumann, Michael
الحاوية / القاعدة Nutrients (2019)

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge

بواسطة Bondar, Constanza, Plaza-Izurieta, Leticia, Fernandez-Jimenez, Nora, Irastorza, Iñaki, Withoff, Sebo, Wijmenga, Cisca, Chirdo, Fernando, Bilbao, Jose Ramon
منشور في 2014

Molecular Biomarkers for Celiac Disease: Past, Present and Future

بواسطة Ramírez-Sánchez, Aarón D., Tan, Ineke L., Gonera-de Jong, B.C., Visschedijk, Marijn C., Jonkers, Iris, Withoff, Sebo
الحاوية / القاعدة Int J Mol Sci (2020)

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

بواسطة Spierings, Diana C., McGoldrick, Daniel, Hamilton-Easton, Ann Marie, Neale, Geoffrey, Murchison, Elizabeth P., Hannon, Greg J., Green, Douglas R., Withoff, Sebo
منشور في 2011

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

بواسطة Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
الحاوية / القاعدة Front Immunol (2019)

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

بواسطة Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
الحاوية / القاعدة J Autoimmun (2020)

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity

بواسطة Hrdlickova, Barbara, Kumar, Vinod, Kanduri, Kartiek, Zhernakova, Daria V, Tripathi, Subhash, Karjalainen, Juha, Lund, Riikka J, Li, Yang, Ullah, Ubaid, Modderman, Rutger, Abdulahad, Wayel, Lähdesmäki, Harri, Franke, Lude, Lahesmaa, Riitta, Wijmenga, Cisca, Withoff, Sebo
الحاوية / القاعدة Genome Med (2014)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

بواسطة Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
منشور في 2013

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

بواسطة Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
الحاوية / القاعدة PLoS One (2017)

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

بواسطة Jaeger, Martin, Matzaraki, Vasiliki, Aguirre-Gamboa, Raúl, Gresnigt, Mark S, Chu, Xiaojing, Johnson, Melissa D, Oosting, Marije, Smeekens, Sanne P, Withoff, Sebo, Jonkers, Iris, Perfect, John R, van de Veerdonk, Frank L, Kullberg, Bart-Jan, Joosten, Leo A B, Li, Yang, Wijmenga, Cisca, Netea, Mihai G, Kumar, Vinod
الحاوية / القاعدة J Infect Dis (2019)

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

بواسطة Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
الحاوية / القاعدة Nat Immunol (2018)

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

بواسطة van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
الحاوية / القاعدة Front Genet (2021)

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

بواسطة Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
الحاوية / القاعدة Sci Rep (2021)

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

بواسطة Almeida, Rodrigo, Ricaño-Ponce, Isis, Kumar, Vinod, Deelen, Patrick, Szperl, Agata, Trynka, Gosia, Gutierrez-Achury, Javier, Kanterakis, Alexandros, Westra, Harm-Jan, Franke, Lude, Swertz, Morris A., Platteel, Mathieu, Bilbao, Jose Ramon, Barisani, Donatella, Greco, Luigi, Mearin, Luisa, Wolters, Victorien M., Mulder, Chris, Mazzilli, Maria Cristina, Sood, Ajit, Cukrowska, Bozena, Núñez, Concepción, Pratesi, Riccardo, Withoff, Sebo, Wijmenga, Cisca
منشور في 2014

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidemia

بواسطة Kumar, Vinod, Cheng, Shih-Chin, Johnson, Melissa D., Smeekens, Sanne P., Wojtowicz, Agnieszka, Giamarellos-Bourboulis, Evangelos, Karjalainen, Juha, Franke, Lude, Withoff, Sebo, Plantinga, Theo S., van de Veerdonk, Frank L., van der Meer, Jos W.M., Joosten, Leo A.B., Bochud, Pierre-Yves, Marchetti, Oscar, Perfect, John R., Xavier, Ramnik, Kullberg, Bart Jan, Wijmenga, Cisca, Netea, Mihai G.
الحاوية / القاعدة Nat Commun (2014)

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

بواسطة Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
الحاوية / القاعدة J Autoimmun (2016)

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease

بواسطة Hrdlickova, Barbara, Mulder, Chris J., Malamut, Georgia, Meresse, Bertrand, Platteel, Mathieu, Kamatani, Yoichiro, Ricaño-Ponce, Isis, van Wanrooij, Roy L.J., Zorro, Maria M., Bonder, Marc Jan, Gutierrez-Achury, Javier, Cellier, Christophe, Zhernakova, Alexandra, Nijeboer, Petula, Galan, Pilar, Withoff, Sebo, Lathrop, Mark, Bouma, Gerd, Xavier, Ramnik J., Jabri, Bana, Bensussan, Nadine C., Wijmenga, Cisca, Kumar, Vinod
الحاوية / القاعدة Eur J Gastroenterol Hepatol (2018)