From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

ανά Kumar, Vinod, Wijmenga, Cisca, Withoff, Sebo
Έκδοση 2012

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

ανά Moerkens, Renée, Mooiweer, Joram, Withoff, Sebo, Wijmenga, Cisca
Τόπος έκδοσης United European Gastroenterol J (2019)

Small and Long Regulatory RNAs in the Immune System and Immune Diseases

ανά Stachurska, Anna, Zorro, Maria M., van der Sijde, Marijke R., Withoff, Sebo
Έκδοση 2014

Intestinal Barrier Function in Gluten-Related Disorders

ανά Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Withoff, Sebo, Branchi, Federica, Schumann, Michael
Τόπος έκδοσης Nutrients (2019)

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge

ανά Bondar, Constanza, Plaza-Izurieta, Leticia, Fernandez-Jimenez, Nora, Irastorza, Iñaki, Withoff, Sebo, Wijmenga, Cisca, Chirdo, Fernando, Bilbao, Jose Ramon
Έκδοση 2014

Molecular Biomarkers for Celiac Disease: Past, Present and Future

ανά Ramírez-Sánchez, Aarón D., Tan, Ineke L., Gonera-de Jong, B.C., Visschedijk, Marijn C., Jonkers, Iris, Withoff, Sebo
Τόπος έκδοσης Int J Mol Sci (2020)

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

ανά Spierings, Diana C., McGoldrick, Daniel, Hamilton-Easton, Ann Marie, Neale, Geoffrey, Murchison, Elizabeth P., Hannon, Greg J., Green, Douglas R., Withoff, Sebo
Έκδοση 2011

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

ανά Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
Τόπος έκδοσης Front Immunol (2019)

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

ανά Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
Τόπος έκδοσης J Autoimmun (2020)

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity

ανά Hrdlickova, Barbara, Kumar, Vinod, Kanduri, Kartiek, Zhernakova, Daria V, Tripathi, Subhash, Karjalainen, Juha, Lund, Riikka J, Li, Yang, Ullah, Ubaid, Modderman, Rutger, Abdulahad, Wayel, Lähdesmäki, Harri, Franke, Lude, Lahesmaa, Riitta, Wijmenga, Cisca, Withoff, Sebo
Τόπος έκδοσης Genome Med (2014)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

ανά Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Έκδοση 2013

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

ανά Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
Τόπος έκδοσης PLoS One (2017)

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

ανά Jaeger, Martin, Matzaraki, Vasiliki, Aguirre-Gamboa, Raúl, Gresnigt, Mark S, Chu, Xiaojing, Johnson, Melissa D, Oosting, Marije, Smeekens, Sanne P, Withoff, Sebo, Jonkers, Iris, Perfect, John R, van de Veerdonk, Frank L, Kullberg, Bart-Jan, Joosten, Leo A B, Li, Yang, Wijmenga, Cisca, Netea, Mihai G, Kumar, Vinod
Τόπος έκδοσης J Infect Dis (2019)

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

ανά Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
Τόπος έκδοσης Nat Immunol (2018)

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

ανά van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
Τόπος έκδοσης Front Genet (2021)

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

ανά Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
Τόπος έκδοσης Sci Rep (2021)

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

ανά Almeida, Rodrigo, Ricaño-Ponce, Isis, Kumar, Vinod, Deelen, Patrick, Szperl, Agata, Trynka, Gosia, Gutierrez-Achury, Javier, Kanterakis, Alexandros, Westra, Harm-Jan, Franke, Lude, Swertz, Morris A., Platteel, Mathieu, Bilbao, Jose Ramon, Barisani, Donatella, Greco, Luigi, Mearin, Luisa, Wolters, Victorien M., Mulder, Chris, Mazzilli, Maria Cristina, Sood, Ajit, Cukrowska, Bozena, Núñez, Concepción, Pratesi, Riccardo, Withoff, Sebo, Wijmenga, Cisca
Έκδοση 2014

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidemia

ανά Kumar, Vinod, Cheng, Shih-Chin, Johnson, Melissa D., Smeekens, Sanne P., Wojtowicz, Agnieszka, Giamarellos-Bourboulis, Evangelos, Karjalainen, Juha, Franke, Lude, Withoff, Sebo, Plantinga, Theo S., van de Veerdonk, Frank L., van der Meer, Jos W.M., Joosten, Leo A.B., Bochud, Pierre-Yves, Marchetti, Oscar, Perfect, John R., Xavier, Ramnik, Kullberg, Bart Jan, Wijmenga, Cisca, Netea, Mihai G.
Τόπος έκδοσης Nat Commun (2014)

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

ανά Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Τόπος έκδοσης J Autoimmun (2016)

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease

ανά Hrdlickova, Barbara, Mulder, Chris J., Malamut, Georgia, Meresse, Bertrand, Platteel, Mathieu, Kamatani, Yoichiro, Ricaño-Ponce, Isis, van Wanrooij, Roy L.J., Zorro, Maria M., Bonder, Marc Jan, Gutierrez-Achury, Javier, Cellier, Christophe, Zhernakova, Alexandra, Nijeboer, Petula, Galan, Pilar, Withoff, Sebo, Lathrop, Mark, Bouma, Gerd, Xavier, Ramnik J., Jabri, Bana, Bensussan, Nadine C., Wijmenga, Cisca, Kumar, Vinod
Τόπος έκδοσης Eur J Gastroenterol Hepatol (2018)