From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

od Kumar, Vinod, Wijmenga, Cisca, Withoff, Sebo
Izdano 2012

Celiac disease-on-chip: Modeling a multifactorial disease in vitro

od Moerkens, Renée, Mooiweer, Joram, Withoff, Sebo, Wijmenga, Cisca
Izdano u United European Gastroenterol J (2019)

Small and Long Regulatory RNAs in the Immune System and Immune Diseases

od Stachurska, Anna, Zorro, Maria M., van der Sijde, Marijke R., Withoff, Sebo
Izdano 2014

Intestinal Barrier Function in Gluten-Related Disorders

od Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Withoff, Sebo, Branchi, Federica, Schumann, Michael
Izdano u Nutrients (2019)

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge

od Bondar, Constanza, Plaza-Izurieta, Leticia, Fernandez-Jimenez, Nora, Irastorza, Iñaki, Withoff, Sebo, Wijmenga, Cisca, Chirdo, Fernando, Bilbao, Jose Ramon
Izdano 2014

Molecular Biomarkers for Celiac Disease: Past, Present and Future

od Ramírez-Sánchez, Aarón D., Tan, Ineke L., Gonera-de Jong, B.C., Visschedijk, Marijn C., Jonkers, Iris, Withoff, Sebo
Izdano u Int J Mol Sci (2020)

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

od Spierings, Diana C., McGoldrick, Daniel, Hamilton-Easton, Ann Marie, Neale, Geoffrey, Murchison, Elizabeth P., Hannon, Greg J., Green, Douglas R., Withoff, Sebo
Izdano 2011

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

od Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
Izdano u Front Immunol (2019)

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

od Zorro, Maria Magdalena, Aguirre-Gamboa, Raul, Mayassi, Toufic, Ciszewski, Cezary, Barisani, Donatella, Hu, Shixian, Weersma, Rinse K, Withoff, Sebo, Li, Yang, Wijmenga, Cisca, Jabri, Bana, Jonkers, Iris H
Izdano u J Autoimmun (2020)

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity

od Hrdlickova, Barbara, Kumar, Vinod, Kanduri, Kartiek, Zhernakova, Daria V, Tripathi, Subhash, Karjalainen, Juha, Lund, Riikka J, Li, Yang, Ullah, Ubaid, Modderman, Rutger, Abdulahad, Wayel, Lähdesmäki, Harri, Franke, Lude, Lahesmaa, Riitta, Wijmenga, Cisca, Withoff, Sebo
Izdano u Genome Med (2014)

Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

od Kumar, Vinod, Westra, Harm-Jan, Karjalainen, Juha, Zhernakova, Daria V., Esko, Tõnu, Hrdlickova, Barbara, Almeida, Rodrigo, Zhernakova, Alexandra, Reinmaa, Eva, Võsa, Urmo, Hofker, Marten H., Fehrmann, Rudolf S. N., Fu, Jingyuan, Withoff, Sebo, Metspalu, Andres, Franke, Lude, Wijmenga, Cisca
Izdano 2013

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

od Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
Izdano u PLoS One (2017)

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

od Jaeger, Martin, Matzaraki, Vasiliki, Aguirre-Gamboa, Raúl, Gresnigt, Mark S, Chu, Xiaojing, Johnson, Melissa D, Oosting, Marije, Smeekens, Sanne P, Withoff, Sebo, Jonkers, Iris, Perfect, John R, van de Veerdonk, Frank L, Kullberg, Bart-Jan, Joosten, Leo A B, Li, Yang, Wijmenga, Cisca, Netea, Mihai G, Kumar, Vinod
Izdano u J Infect Dis (2019)

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

od Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
Izdano u Nat Immunol (2018)

Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease

od van der Graaf, Adriaan, Zorro, Maria M., Claringbould, Annique, Võsa, Urmo, Aguirre-Gamboa, Raúl, Li, Chan, Mooiweer, Joram, Ricaño-Ponce, Isis, Borek, Zuzanna, Koning, Frits, Kooy-Winkelaar, Yvonne, Sollid, Ludvig M., Qiao, Shuo-Wang, Kumar, Vinod, Li, Yang, Franke, Lude, Withoff, Sebo, Wijmenga, Cisca, Sanna, Serena, Jonkers, Iris
Izdano u Front Genet (2021)

Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells

od Bakker, Olivier B., Ramírez-Sánchez, Aarón D., Borek, Zuzanna A., de Klein, Niek, Li, Yang, Modderman, Rutger, Kooy-Winkelaar, Yvonne, Johannesen, Marie K., Matarese, Filomena, Martens, Joost H. A., Kumar, Vinod, van Bergen, Jeroen, Qiao, Shuo-Wang, Lundin, Knut E. A., Sollid, Ludvig M., Koning, Frits, Wijmenga, Cisca, Withoff, Sebo, Jonkers, Iris H.
Izdano u Sci Rep (2021)

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

od Almeida, Rodrigo, Ricaño-Ponce, Isis, Kumar, Vinod, Deelen, Patrick, Szperl, Agata, Trynka, Gosia, Gutierrez-Achury, Javier, Kanterakis, Alexandros, Westra, Harm-Jan, Franke, Lude, Swertz, Morris A., Platteel, Mathieu, Bilbao, Jose Ramon, Barisani, Donatella, Greco, Luigi, Mearin, Luisa, Wolters, Victorien M., Mulder, Chris, Mazzilli, Maria Cristina, Sood, Ajit, Cukrowska, Bozena, Núñez, Concepción, Pratesi, Riccardo, Withoff, Sebo, Wijmenga, Cisca
Izdano 2014

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidemia

od Kumar, Vinod, Cheng, Shih-Chin, Johnson, Melissa D., Smeekens, Sanne P., Wojtowicz, Agnieszka, Giamarellos-Bourboulis, Evangelos, Karjalainen, Juha, Franke, Lude, Withoff, Sebo, Plantinga, Theo S., van de Veerdonk, Frank L., van der Meer, Jos W.M., Joosten, Leo A.B., Bochud, Pierre-Yves, Marchetti, Oscar, Perfect, John R., Xavier, Ramnik, Kullberg, Bart Jan, Wijmenga, Cisca, Netea, Mihai G.
Izdano u Nat Commun (2014)

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

od Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Izdano u J Autoimmun (2016)

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease

od Hrdlickova, Barbara, Mulder, Chris J., Malamut, Georgia, Meresse, Bertrand, Platteel, Mathieu, Kamatani, Yoichiro, Ricaño-Ponce, Isis, van Wanrooij, Roy L.J., Zorro, Maria M., Bonder, Marc Jan, Gutierrez-Achury, Javier, Cellier, Christophe, Zhernakova, Alexandra, Nijeboer, Petula, Galan, Pilar, Withoff, Sebo, Lathrop, Mark, Bouma, Gerd, Xavier, Ramnik J., Jabri, Bana, Bensussan, Nadine C., Wijmenga, Cisca, Kumar, Vinod
Izdano u Eur J Gastroenterol Hepatol (2018)