The MHC locus and genetic susceptibility to autoimmune and infectious diseases

par Matzaraki, Vasiliki, Kumar, Vinod, Wijmenga, Cisca, Zhernakova, Alexandra
Publié dans Genome Biol (2017)

Functional Annotation of Genetic Loci Associated With Sepsis Prioritizes Immune and Endothelial Cell Pathways

par Le, Kieu T. T., Matzaraki, Vasiliki, Netea, Mihai G., Wijmenga, Cisca, Moser, Jill, Kumar, Vinod
Publié dans Front Immunol (2019)

Challenges and Opportunities in Understanding Genetics of Fungal Diseases: Towards a Functional Genomics Approach

par Bruno, Mariolina, Matzaraki, Vasiliki, van de Veerdonk, Frank L., Kumar, Vinod, Netea, Mihai G.
Publié dans Infect Immun (2021)

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

par de Vries, Dylan H., Matzaraki, Vasiliki, Bakker, Olivier B., Brugge, Harm, Westra, Harm-Jan, Netea, Mihai G., Franke, Lude, Kumar, Vinod, van der Wijst, Monique G. P.
Publié dans PLoS Pathog (2020)

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells

par Le, Kieu T. T., Chu, Xiaojing, Jaeger, Martin, Plantinga, Josée A., Matzaraki, Vasiliki, Withoff, Sebo, Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Li, Yang, Moser, Jill, Kumar, Vinod
Publié dans Front Immunol (2019)

Inter-individual variability and genetic influences on cytokine responses against bacterial and fungal pathogens

par Li, Yang, Oosting, Marije, Deelen, Patrick, Ricaño-Ponce, Isis, Smeekens, Sanne, Jaeger, Martin, Matzaraki, Vasiliki, Swertz, Morris A., Xavier, Ramnik J., Franke, Lude, Wijmenga, Cisca, Joosten, Leo A.B., Kumar, Vinod, Netea, Mihai G.
Publié dans Nat Med (2016)

Tissue Metabolic Changes Drive Cytokine Responses to Mycobacterium tuberculosis

par Lachmandas, Ekta, Rios-Miguel, Ana B, Koeken, Valerie A C M, van der Pasch, Eva, Kumar, Vinod, Matzaraki, Vasiliki, Li, Yang, Oosting, Marije, Joosten, Leo A B, Notebaart, Richard A, Noursadeghi, Mahdad, Netea, Mihai G, van Crevel, Reinout, Pollara, Gabriele
Publié dans J Infect Dis (2018)

Glutathione Metabolism Contributes to the Induction of Trained Immunity

par Ferreira, Anaisa V., Koeken, Valerie A. C. M., Matzaraki, Vasiliki, Kostidis, Sarantos, Alarcon-Barrera, Juan Carlos, de Bree, L. Charlotte J., Moorlag, Simone J. C. F. M., Mourits, Vera P., Novakovic, Boris, Giera, Martin A., Netea, Mihai G., Domínguez-Andrés, Jorge
Publié dans Cells (2021)

An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility

par Matzaraki, Vasiliki, Gresnigt, Mark S., Jaeger, Martin, Ricaño-Ponce, Isis, Johnson, Melissa D., Oosting, Marije, Franke, Lude, Withoff, Sebo, Perfect, John R., Joosten, Leo A. B., Kullberg, Bart Jan, van de Veerdonk, Frank L., Jonkers, Iris, Li, Yang, Wijmenga, Cisca, Netea, Mihai G., Kumar, Vinod
Publié dans PLoS One (2017)

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans

par Jaeger, Martin, Matzaraki, Vasiliki, Aguirre-Gamboa, Raúl, Gresnigt, Mark S, Chu, Xiaojing, Johnson, Melissa D, Oosting, Marije, Smeekens, Sanne P, Withoff, Sebo, Jonkers, Iris, Perfect, John R, van de Veerdonk, Frank L, Kullberg, Bart-Jan, Joosten, Leo A B, Li, Yang, Wijmenga, Cisca, Netea, Mihai G, Kumar, Vinod
Publié dans J Infect Dis (2019)

The role of Toll‐like receptor 10 in modulation of trained immunity

par Mourits, Vera P., Arts, Rob J.W., Novakovic, Boris, Matzaraki, Vasiliki, de Bree, L. Charlotte J., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., van Puffelen, Jelmer H., Groh, Laszlo, van der Heijden, Charlotte D.C.C., Keating, Sam T., Netea, Mihai G., Oosting, Marije, Joosten, Leo A.B.
Publié dans Immunology (2019)

oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming

par Groh, Laszlo A., Ferreira, Anaisa V., Helder, Leonie, van der Heijden, Charlotte D. C. C., Novakovic, Boris, van de Westerlo, Els, Matzaraki, Vasiliki, Moorlag, Simone J. C. F. M., de Bree, L. Charlotte, Koeken, Valerie A. C. M., Mourits, Vera P., Keating, Samuel T., van Puffelen, Jelmer H., Hoischen, Alexander, Joosten, Leo A. B., Netea, Mihai G., Koopman, Werner J. H., Riksen, Niels P.
Publié dans Immunometabolism (2021)

Tetraspanin CD82 organizes Dectin-1 into signaling domains to mediate cellular responses to Candida albicans

par Tam, Jenny M, Reedy, Jennifer L, Lukason, Daniel P, Kuna, Sunnie G, Acharya, Mridu, Khan, Nida S, Negoro, Paige E, Xu, Linda, Ward, Rebecca A, Feldman, Michael B, Dutko, Richard A, Jeffery, Jane B, Sokolovska, Anna, Wivagg, Carl N, Lassen, Kara G, Le Naour, Françios, Matzaraki, Vasiliki, Garner, Ethan C, Xavier, Ramnik J, Kumar, Vinod, van de Veerdonk, Frank L, Netea, Mihai G, Miranti, Cindy K, Mansour, Michael K, Vyas, Jatin M
Publié dans J Immunol (2019)

Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

par Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Strienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Publié dans J Mol Med (Berl) (2020)

Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein

par Keating, Samuel T., Groh, Laszlo, Thiem, Kathrin, Bekkering, Siroon, Li, Yang, Matzaraki, Vasiliki, van der Heijden, Charlotte D. C. C., van Puffelen, Jelmer H., Lachmandas, Ekta, Jansen, Trees, Oosting, Marije, de Bree, L. Charlotte J., Koeken, Valerie A. C. M., Moorlag, Simone J. C. F. M., Mourits, Vera P., van Diepen, Janna, Stienstra, Rinke, Novakovic, Boris, Stunnenberg, Hendrik G., van Crevel, Reinout, Joosten, Leo A. B., Netea, Mihai G., Riksen, Niels P.
Publié dans J Mol Med (Berl) (2020)

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

par Keating, Samuel T., Groh, Laszlo, van der Heijden, Charlotte D.C.C., Rodriguez, Hanah, dos Santos, Jéssica C., Fanucchi, Stephanie, Okabe, Jun, Kaipananickal, Harikrishnan, van Puffelen, Jelmer H., Helder, Leonie, Noz, Marlies P., Matzaraki, Vasiliki, Li, Yang, de Bree, L. Charlotte J., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Mourits, Vera P., Domínguez-Andrés, Jorge, Oosting, Marije, Bulthuis, Elianne P., Koopman, Werner J.H., Mhlanga, Musa, El-Osta, Assam, Joosten, Leo A.B., Netea, Mihai G., Riksen, Niels P.
Publié dans Cell Rep (2020)

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

par Janssen, Nico A F, Grondman, Inge, de Nooijer, Aline H, Boahen, Collins K, Koeken, Valerie A C M, Matzaraki, Vasiliki, Kumar, Vinod, He, Xuehui, Kox, Matthijs, Koenen, Hans J P M, Smeets, Ruben L, Joosten, Irma, Brüggemann, Roger J M, Kouijzer, Ilse J E, van der Hoeven, Hans G, Schouten, Jeroen A, Frenzel, Tim, Reijers, Monique, Hoefsloot, Wouter, Dofferhoff, Anton S M, van Apeldoorn, Marjan J, Blaauw, Marc J T, Veerman, Karin, Maas, Coen, Schoneveld, Arjan H, Hoefer, Imo E, Derde, Lennie P G, van Deuren, Marcel, van der Meer, Jos W M, van Crevel, Reinout, Giamarellos-Bourboulis, Evangelos J, Joosten, Leo A B, van den Heuvel, Michel M, Hoogerwerf, Jacobien, de Mast, Quirijn, Pickkers, Peter, Netea, Mihai G, van de Veerdonk, Frank L
Publié dans J Infect Dis (2021)