Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

Candida bloodstream infection, i.e. candidemia, is the most frequently encountered life-threatening fungal infection worldwide, with mortality rates up to almost 50%. In the majority of candidemia cases, Candida albicans is responsible. Worryingly, a global increase in the number of patients who are...

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發表在:PLoS Pathog
Main Authors: de Vries, Dylan H., Matzaraki, Vasiliki, Bakker, Olivier B., Brugge, Harm, Westra, Harm-Jan, Netea, Mihai G., Franke, Lude, Kumar, Vinod, van der Wijst, Monique G. P.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173933/
https://ncbi.nlm.nih.gov/pubmed/32251450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008408
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