Tissue Metabolic Changes Drive Cytokine Responses to Mycobacterium tuberculosis

Cellular metabolism can influence host immune responses to Mycobacterium tuberculosis. Using a systems biology approach, differential expression of 292 metabolic genes involved in glycolysis, glutathione, pyrimidine, and inositol phosphate pathways was evident at the site of a human tuberculin skin...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Lachmandas, Ekta, Rios-Miguel, Ana B, Koeken, Valerie A C M, van der Pasch, Eva, Kumar, Vinod, Matzaraki, Vasiliki, Li, Yang, Oosting, Marije, Joosten, Leo A B, Notebaart, Richard A, Noursadeghi, Mahdad, Netea, Mihai G, van Crevel, Reinout, Pollara, Gabriele
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989606/
https://ncbi.nlm.nih.gov/pubmed/29618104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy173
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