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The MHC locus and genetic susceptibility to autoimmune and infectious diseases

In the past 50 years, variants in the major histocompatibility complex (MHC) locus, also known as the human leukocyte antigen (HLA), have been reported as major risk factors for complex diseases. Recent advances, including large genetic screens, imputation, and analyses of non-additive and epistatic...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Matzaraki, Vasiliki, Kumar, Vinod, Wijmenga, Cisca, Zhernakova, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406920/
https://ncbi.nlm.nih.gov/pubmed/28449694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1207-1
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