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Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
Although dietary gluten is the trigger, celiac disease risk is strongly influenced by genetic variation in the major histocompatibility complex (MHC) region. We fine-mapped the MHC association signal to identify additional risk factors independent of the HLA-DQ alleles and observed five novel associ...
Tallennettuna:
| Julkaisussa: | Nat Genet |
|---|---|
| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449296/ https://ncbi.nlm.nih.gov/pubmed/25894500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3268 |
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