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oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming

Following brief exposure to endogenous atherogenic particles, such as oxidized low-density lipoprotein (oxLDL), monocytes/macrophages can adopt a long-term pro-inflammatory phenotype, which is called trained immunity. This mechanism might contribute to the chronic low-grade inflammation that charact...

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Bibliografske podrobnosti
izdano v:Immunometabolism
Main Authors: Groh, Laszlo A., Ferreira, Anaisa V., Helder, Leonie, van der Heijden, Charlotte D. C. C., Novakovic, Boris, van de Westerlo, Els, Matzaraki, Vasiliki, Moorlag, Simone J. C. F. M., de Bree, L. Charlotte, Koeken, Valerie A. C. M., Mourits, Vera P., Keating, Samuel T., van Puffelen, Jelmer H., Hoischen, Alexander, Joosten, Leo A. B., Netea, Mihai G., Koopman, Werner J. H., Riksen, Niels P.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611242/
https://ncbi.nlm.nih.gov/pubmed/34267957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20210025
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