oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming

Following brief exposure to endogenous atherogenic particles, such as oxidized low-density lipoprotein (oxLDL), monocytes/macrophages can adopt a long-term pro-inflammatory phenotype, which is called trained immunity. This mechanism might contribute to the chronic low-grade inflammation that charact...

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Publicado no:Immunometabolism
Main Authors: Groh, Laszlo A., Ferreira, Anaisa V., Helder, Leonie, van der Heijden, Charlotte D. C. C., Novakovic, Boris, van de Westerlo, Els, Matzaraki, Vasiliki, Moorlag, Simone J. C. F. M., de Bree, L. Charlotte, Koeken, Valerie A. C. M., Mourits, Vera P., Keating, Samuel T., van Puffelen, Jelmer H., Hoischen, Alexander, Joosten, Leo A. B., Netea, Mihai G., Koopman, Werner J. H., Riksen, Niels P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611242/
https://ncbi.nlm.nih.gov/pubmed/34267957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20210025
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