Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

The immune response to pathogens varies substantially among people. While both genetic and non-genetic factors contribute to inter-person variation, their relative contributions and potential predictive power have remained largely unknown. By systematically correlating host factors in 534 healthy vo...

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Veröffentlicht in:Nat Immunol
Hauptverfasser: Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J.P.M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A.B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G., Li, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022810/
https://ncbi.nlm.nih.gov/pubmed/29784908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0121-3
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