Nucleotide Excision DNA Repair is Associated with Age-Related Vascular Dysfunction

BACKGROUND: Vascular dysfunction in atherosclerosis and diabetes, as observed in the aging population of developed societies, is associated with vascular DNA damage and cell senescence. We hypothesized that cumulative DNA damage during aging contributes to vascular dysfunction. METHODS AND RESULTS:...

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में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Durik, Matej, Kavousi, Maryam, van der Pluijm, Ingrid, Isaacs, Aaron, Cheng, Caroline, Verdonk, Koen, Loot, Annemarieke E., Oeseburg, Hisko, Musterd-Bhaggoe, Usha, Leijten, Frank, van Veghel, Richard, de Vries, Rene, Rudez, Goran, Brandt, Renata, Ridwan, Yanto R., van Deel, Elza D., de Boer, Martine, Tempel, Dennie, Fleming, Ingrid, Mitchell, Gary F., Verwoert, Germaine C., Tarasov, Kirill V., Uitterlinden, Andre G., Hofman, Albert, Duckers, Henricus J., van Duijn, Cornelia M., Oostra, Ben A., Witteman, Jacqueline C.M., Duncker, Dirk J., Danser, A.H. Jan, Hoeijmakers, Jan H., Roks, Anton J.M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430727/
https://ncbi.nlm.nih.gov/pubmed/22705887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.104380
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