Association of the IGF1 gene with fasting insulin levels

Insulin-like growth factor 1 (IGF-I) has been associated with insulin resistance. Genome-wide association studies (GWASs) of fasting insulin (FI) identified single-nucleotide variants (SNVs) near the IGF1 gene, raising two hypotheses: (1) these associations are mediated by IGF-I levels and (2) these...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Willems, Sara M, Cornes, Belinda K, Brody, Jennifer A, Morrison, Alanna C, Lipovich, Leonard, Dauriz, Marco, Chen, Yuning, Liu, Ching-Ti, Rybin, Denis V, Gibbs, Richard A, Muzny, Donna, Pankow, James S, Psaty, Bruce M, Boerwinkle, Eric, Rotter, Jerome I, Siscovick, David S, Vasan, Ramachandran S, Kaplan, Robert C, Isaacs, Aaron, Dupuis, Josée, van Duijn, Cornelia M, Meigs, James B
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989214/
https://ncbi.nlm.nih.gov/pubmed/26860063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.4
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