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Association of the IGF1 gene with fasting insulin levels

Insulin-like growth factor 1 (IGF-I) has been associated with insulin resistance. Genome-wide association studies (GWASs) of fasting insulin (FI) identified single-nucleotide variants (SNVs) near the IGF1 gene, raising two hypotheses: (1) these associations are mediated by IGF-I levels and (2) these...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Willems, Sara M, Cornes, Belinda K, Brody, Jennifer A, Morrison, Alanna C, Lipovich, Leonard, Dauriz, Marco, Chen, Yuning, Liu, Ching-Ti, Rybin, Denis V, Gibbs, Richard A, Muzny, Donna, Pankow, James S, Psaty, Bruce M, Boerwinkle, Eric, Rotter, Jerome I, Siscovick, David S, Vasan, Ramachandran S, Kaplan, Robert C, Isaacs, Aaron, Dupuis, Josée, van Duijn, Cornelia M, Meigs, James B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989214/
https://ncbi.nlm.nih.gov/pubmed/26860063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.4
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