HLA Class I and II alleles, heterozygosity and HLA-KIR interactions are associated with rates of genital HSV shedding and lesions

Variation at HLA and KIR loci is associated with the severity of viral infections. To assess associations of genital HSV-2 infection with human HLA and KIR genetic loci, we measured the frequencies of genital HSV DNA detection and of genital lesions in HSV-2 seropositive persons. We followed 267 HSV...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Magaret, Amalia, Dong, Lichun, John, Mina, Mallal, Simon A., James, Ian, Warren, Terri, Gaudieri, Silvana, Koelle, David M., Wald, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133162/
https://ncbi.nlm.nih.gov/pubmed/27853144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.42
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