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Recent advances in the diagnosis and treatment of heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a drug-mediated, prothrombotic disorder caused by immunization against platelet factor 4 (PF4) after complex formation with heparin or other polyanions. After their binding to PF4/heparin complexes on the platelet surface, HIT antibodies are capable of intra...

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Detalhes bibliográficos
Main Authors: Bakchoul, Tamam, Greinacher, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627332/
https://ncbi.nlm.nih.gov/pubmed/23606934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620712443537
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