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Recent advances in the diagnosis and treatment of heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a drug-mediated, prothrombotic disorder caused by immunization against platelet factor 4 (PF4) after complex formation with heparin or other polyanions. After their binding to PF4/heparin complexes on the platelet surface, HIT antibodies are capable of intra...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627332/ https://ncbi.nlm.nih.gov/pubmed/23606934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620712443537 |
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