MDM2 and MDM4: p53 regulators as targets in anticancer therapy

Autor Toledo, Franck, Wahl, Geoffrey M.
Vydáno 2007

Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

Autor Wade, Mark, Wahl, Geoffrey M.
Vydáno 2009

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome

Autor Spike, Benjamin T., Wahl, Geoffrey M.
Vydáno 2011

Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

Autor Wahl, Geoffrey M., Spike, Benjamin T.
Vydáno v NPJ Breast Cancer (2017)

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation

Autor Stommel, Jayne M, Wahl, Geoffrey M
Vydáno 2004

Coupling of Mitotic Chromosome Tethering and Replication Competence in Epstein-Barr Virus-Based Plasmids

Autor Kanda, Teru, Otter, Michele, Wahl, Geoffrey M.
Vydáno 2001

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

Autor Khan, Shireen Hussain, Moritsugu, Janet, Wahl, Geoffrey M.
Vydáno 2000

Guarding the Guardian: Mdmx plays important roles in setting p53 basal activity and determining biological responses in vivo

Autor Wang, Yunyuan V., Wade, Mark, Wahl, Geoffrey M.
Vydáno 2009

The p53 orchestra: Mdm2 and Mdmx set the tone

Autor Wade, Mark, Wang, Yunyuan V., Wahl, Geoffrey M.
Vydáno 2010

MDM2, MDMX and p53 in oncogenesis and cancer therapy

Autor Wade, Mark, Li, Yao-Cheng, Wahl, Geoffrey M.
Vydáno 2013

Metaphase Chromosome Tethering Is Necessary for the DNA Synthesis and Maintenance of oriP Plasmids but Is Insufficient for Transcription Activation by Epstein-Barr Nuclear Antigen...

Autor Sears, John, Kolman, John, Wahl, Geoffrey M., Aiyar, Ashok
Vydáno 2003

Metaphase Chromosome Tethering Is Necessary for the DNA Synthesis and Maintenance of oriP Plasmids but Is Insufficient for Transcription Activation by Epstein-Barr Nuclear Antigen...

Autor Sears, John, Kolman, John, Wahl, Geoffrey M., Aiyar, Ashok
Vydáno 2004

Selective Entrapment of Extrachromosomally Amplified DNA by Nuclear Budding and Micronucleation during S Phase

Autor Shimizu, Noriaki, Itoh, Nobuo, Utiyama, Hiroyasu, Wahl, Geoffrey M.
Vydáno 1998

A critical examination of the “bad luck” explanation of cancer risk

Autor Rozhok, Andrii I., Wahl, Geoffrey M., DeGregori, James
Vydáno v Cancer Prev Res (Phila) (2015)

Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures

Autor Mizuno, Hideaki, Spike, Benjamin T., Wahl, Geoffrey M., Levine, Arnold J.
Vydáno 2010

Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage

Autor Paulson, Thomas G., Almasan, Alexandru, Brody, Linnea L., Wahl, Geoffrey M.
Vydáno 1998

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

Autor Krummel, Kurt A., Lee, Crystal J., Toledo, Franck, Wahl, Geoffrey M.
Vydáno 2005

RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses

Autor Toledo, Franck, Liu, Chung-Wen, Lee, Crystal J., Wahl, Geoffrey M.
Vydáno 2006

BH3 activation blocks Hdmx suppression of apoptosis and co-operates with Nutlin to induce cell death

Autor Wade, Mark, Rodewald, Luo Wei, Espinosa, Joaquín M., Wahl, Geoffrey M.
Vydáno 2008

Selective Degradation of Abnormal Proteins in Mammalian Tissue Culture Cells

Autor Capecchi, Mario R., Capecchi, Nancy E., Hughes, Stephen H., Wahl, Geoffrey M.
Vydáno 1974