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p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome

p53 is well recognized as a potent tumor suppressor. In its classic role, p53 responds to genotoxic insults by inducing cell cycle exit or programmed cell death to limit the propagation of cells with corrupted genomes. p53 is also implicated in a variety of other cellular processes in which its invo...

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Detalhes bibliográficos
Main Authors: Spike, Benjamin T., Wahl, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135646/
https://ncbi.nlm.nih.gov/pubmed/21779509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911410224
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