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Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

Genomic and proteomic profiling of human tumor samples and tumor-derived cell lines are essential for the realization of personalized therapy in oncology. Identification of the changes required for tumor initiation or maintenance will likely provide new targets for small molecule and biologic therap...

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Detalles Bibliográficos
Main Authors: Wade, Mark, Wahl, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629357/
https://ncbi.nlm.nih.gov/pubmed/19147532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0423
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