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Targeting p53-MDM2-MDMX Loop for Cancer Therapy

The tumor suppressor p53 plays a central role in anti-tumorigenesis and cancer therapy. It has been described as “the guardian of the genome”, because it is essential for conserving genomic stability by preventing mutation, and its mutation and inactivation are highly related to all human cancers. T...

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Dades bibliogràfiques
Publicat a:Subcell Biochem
Autors principals: Zhang, Qi, Zeng, Shelya X., Lu, Hua
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472007/
https://ncbi.nlm.nih.gov/pubmed/25201201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-017-9211-0_16
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