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Stochastic Modeling and Simulation of the p53-MDM2/MDMX Loop
The p53 gene is crucial for effective tumor suppression in humans as supported by its universal inactivation in cancer cells either through mutations affecting the p53 locus directly or through aberration of its normal regulation. The p53 tumor repressor is regulated through a negative feedback loop...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148126/ https://ncbi.nlm.nih.gov/pubmed/19580521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2008.0231 |
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