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Targeting p53-MDM2-MDMX Loop for Cancer Therapy

The tumor suppressor p53 plays a central role in anti-tumorigenesis and cancer therapy. It has been described as “the guardian of the genome”, because it is essential for conserving genomic stability by preventing mutation, and its mutation and inactivation are highly related to all human cancers. T...

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Detalles Bibliográficos
Publicado en:Subcell Biochem
Main Authors: Zhang, Qi, Zeng, Shelya X., Lu, Hua
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472007/
https://ncbi.nlm.nih.gov/pubmed/25201201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-017-9211-0_16
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