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Targeting p53-MDM2-MDMX Loop for Cancer Therapy
The tumor suppressor p53 plays a central role in anti-tumorigenesis and cancer therapy. It has been described as “the guardian of the genome”, because it is essential for conserving genomic stability by preventing mutation, and its mutation and inactivation are highly related to all human cancers. T...
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| Pubblicato in: | Subcell Biochem |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472007/ https://ncbi.nlm.nih.gov/pubmed/25201201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-017-9211-0_16 |
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