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Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner
Although p53 is not essential for normal embryonic development, it plays a pivotal role in many biological and pathological processes, including cell fate determination-dependent and independent events and diseases. The expression and activity of p53 largely depend on its two biological inhibitors,...
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| Опубликовано в: : | Dev Biol |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328981/ https://ncbi.nlm.nih.gov/pubmed/28118981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.01.014 |
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