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The p53 orchestra: Mdm2 and Mdmx set the tone
The activities of p53 cover diverse aspects of cell biology, including cell cycle control, apoptosis, metabolism, fertility, differentiation and cellular reprogramming. Although loss of p53 function engenders tumor susceptibility, hyperactivation of p53 is lethal. Therefore, p53 activity must be str...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910097/ https://ncbi.nlm.nih.gov/pubmed/20172729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.01.009 |
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