A Perspective on Vascular Disrupting Agents that Interact with Tubulin: Preclinical Tumor Imaging and Biological Assessment

nork Mason, Ralph P., Zhao, Dawen, Liu, Li, Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2011

Application of the McMurry Coupling Reaction in the Synthesis of Tri- and Tetra-arylethylene Analogues as Potential Cancer Chemotherapeutic Agents

nork Tanpure, Rajendra P., Harkrider, Amanda R., Strecker, Tracy E., Hamel, Ernest, Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2009

Synthesis and biological evaluation of structurally diverse α-conformationally restricted chalcones and related analogues

nork Maguire, Casey J., Carlson, Graham J., Ford, Jacob W., Strecker, Tracy E., Hamel, Ernest, Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Medchemcomm (2019)

Non-Invasive Evaluation of Acute Effects of Tubulin Binding Agents: A Review of Imaging Vascular Disruption in Tumors †

nork Liu, Li, O’Kelly, Devin, Schuetze, Regan, Carlson, Graham, Zhou, Heling, Trawick, Mary Lynn, Pinney, Kevin G., Mason, Ralph P.
Argitaratua izan da Molecules (2021)

An Amino-Benzosuberene Analogue That Inhibits Tubulin Assembly and Demonstrates Remarkable Cytotoxicity

nork Tanpure, Rajendra P., George, Clinton S., Sriram, Madhavi, Strecker, Tracy E., Tidmore, Justin K., Hamel, Ernest, Charlton-Sevcik, Amanda K., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2012

Evaluation of tumor ischemia in response to an indole-based vascular disrupting agent using BLI and (19)F MRI

nork Zhou, Heling, Hallac, Rami R, Lopez, Ramona, Denney, Rebecca, MacDonough, Matthew T, Li, Li, Liu, Li, Graves, Edward E, Trawick, Mary Lynn, Pinney, Kevin G, Mason, Ralph P
Argitaratua izan da Am J Nucl Med Mol Imaging (2015)

Structure Guided Design, Synthesis and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

nork Niu, Haichan, Strecker, Tracy E., Gerberich, Jeni L., Campbell, James W., Saha, Debabrata, Mondal, Deboprosad, Hamel, Ernest, Chaplin, David J., Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da J Med Chem (2019)

Synthesis and Biological Evaluation of Benzocyclooctene-based and Indene-based Anticancer Agents that Function as Inhibitors of Tubulin Polymerization()

nork Herdman, Christine A., Strecker, Tracy E., Tanpure, Rajendra P., Chen, Zhi, Winters, Alex, Gerberich, Jeni, Liu, Li, Hamel, Ernest, Mason, Ralph P., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Medchemcomm (2016)

Synthesis and Biochemical Evaluation of Thiochromanone Thiosemicarbazone Analogues as Inhibitors of Cathepsin L

nork Song, Jiangli, Jones, Lindsay M., Kumar, G. D. Kishore, Conner, Elizabeth S., Bayeh, Liela, Chavarria, Gustavo E., Charlton-Sevcik, Amanda K., Chen, Shen-En, Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2012

Regioselective Synthesis of Water Soluble Monophosphate Derivatives of Combretastatin A-1

nork Tanpure, Rajendra P., Nguyen, Benson L., Strecker, Tracy E., Aguirre, Savannah, Sharma, Suman, Chaplin, David J., Siim, Bronwyn G., Hamel, Ernest, Lippert, John W., Pettit, George R., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2011

Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents

nork Tanpure, Rajendra P., George, Clinton S., Strecker, Tracy E., Devkota, Laxman, Tidmore, Justin K., Lin, Chen-Ming, Herdman, Christine A., MacDonough, Matthew T., Sriram, Madhavi, Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2013

Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents

nork Maguire, Casey J., Chen, Zhi, Mocharla, Vani P., Sriram, Madhavi, Strecker, Tracy E., Hamel, Ernest, Zhou, Heling, Lopez, Ramona, Wang, Yifan, Mason, Ralph P., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Medchemcomm (2018)

Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors

nork Kishore Kumar, G.D., Chavarria, Gustavo E., Charlton-Sevcik, Amanda K., Arispe, Wara M., MacDonough, Matthew T., Strecker, Tracy E., Chen, Shen-En, Siim, Bronwyn G., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Bioorg Med Chem Lett (2010)

Structural Interrogation of Benzosuberene-Based Inhibitors of Tubulin Polymerization

nork Herdman, Christine A., Devkota, Laxman, Lin, Chen-Ming, Niu, Haichan, Strecker, Tracy E., Lopez, Ramona, Liu, Li, George, Clinton S., Tanpure, Rajendra P., Hamel, Ernest, Chaplin, David J., Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Bioorg Med Chem (2015)

Design, Synthesis, and Biological Evaluation of Water-Soluble Amino Acid Prodrug Conjugates Derived from Combretastatin, Dihydronaphthalene, and Benzosuberene-Based Parent Vascular...

nork Devkota, Laxman, Lin, Chen-Ming, Strecker, Tracy E., Wang, Yifan, Tidmore, Justin K., Chen, Zhi, Guddneppanavar, Rajsekhar, Jelinek, Christopher J., Lopez, Ramona, Liu, Li, Hamel, Ernest, Mason, Ralph P., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Bioorg Med Chem (2016)

The Vascular Disrupting Activity of OXi8006 in Endothelial Cells and Its Phosphate Prodrug OXi8007 in Breast Tumor Xenografts

nork Strecker, Tracy E., Odutola, Samuel O., Lopez, Ramona, Cooper, Morgan S., Tidmore, Justin K., Charlton-Sevcik, Amanda K., Li, Li, MacDonough, Matthew T., Hadimani, Mallinath B., Ghatak, Anjan, Liu, Li, Chaplin, David J., Mason, Ralph P., Pinney, Kevin G., Trawick, Mary Lynn
Argitaratua izan da Cancer Lett (2015)

Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted Towards Tumor-Associated Hypoxia

nork Winn, Blake A., Devkota, Laxman, Kuch, Bunnarack, MacDonough, Matthew T., Strecker, Tracy E., Wang, Yifan, Shi, Zhe, Gerberich, Jeni L., Mondal, Deboprosad, Ramirez, Alejandro J., Hamel, Ernest, Chaplin, David J., Davis, Peter, Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da J Nat Prod (2020)

Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L

nork Parker, Erica N., Song, Jiangli, Kumar, G. D. Kishore, Odutola, Samuel O., Chavarria, Gustavo E., Charlton-Sevcik, Amanda K., Strecker, Tracy E., Barnes, Ashleigh L., Sudhan, Dhivya R., Wittenborn, Thomas R., Siemann, Dietmar W., Horsman, Michael R., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua izan da Bioorg Med Chem (2015)

Synthesis of a 2-Aryl-3-Aroyl-Indole Salt (OXi8007) Resembling Combretastatin A-4 with Application as a Vascular Disrupting Agent

nork Hadimani, Mallinath B., MacDonough, Matthew T., Ghatak, Anjan, Strecker, Tracy E., Lopez, Ramona, Sriram, Madhavi, Nguyen, Benson L., Hall, John J., Kessler, Raymond J., Shirali, Anupama R., Liu, Li, Garner, Charles M., Pettit, George R., Hamel, Ernest, Chaplin, David J., Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.
Argitaratua 2013