Non-Invasive Evaluation of Acute Effects of Tubulin Binding Agents: A Review of Imaging Vascular Disruption in Tumors †

Tumor vasculature proliferates rapidly, generally lacks pericyte coverage, and is uniquely fragile making it an attractive therapeutic target. A subset of small-molecule tubulin binding agents cause disaggregation of the endothelial cytoskeleton leading to enhanced vascular permeability generating i...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Liu, Li, O’Kelly, Devin, Schuetze, Regan, Carlson, Graham, Zhou, Heling, Trawick, Mary Lynn, Pinney, Kevin G., Mason, Ralph P.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125421/
https://ncbi.nlm.nih.gov/pubmed/33925707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092551
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