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Application of the McMurry Coupling Reaction in the Synthesis of Tri- and Tetra-arylethylene Analogues as Potential Cancer Chemotherapeutic Agents

Structural redesign of selected non-steroidal estrogen receptor binding compounds has previously been successful in the discovery of new inhibitors of tubulin assembly. Accordingly, tetra-substituted alkene analogues (21-30) were designed based in part on combinations of the structural and electroni...

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Bibliografische gegevens
Hoofdauteurs: Tanpure, Rajendra P., Harkrider, Amanda R., Strecker, Tracy E., Hamel, Ernest, Trawick, Mary Lynn, Pinney, Kevin G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935255/
https://ncbi.nlm.nih.gov/pubmed/19733085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.08.011
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