2-Carbaborane-3-phenyl-1H-indoles – Synthesis via McMurry Reaction and COX Inhibition Activity

Cyclooxygenase-2 (COX-2) inhibitors have been in the focus of medicinal chemistry for years and many compounds exhibiting high selectivity and affinity were developed. As carbaboranes represent interesting pharmacophores as phenyl mimetics in drug development, this paper presents the synthesis of ca...

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Bibliografiske detaljer
Main Authors: Laube, Markus, Neumann, Wilma, Scholz, Matthias, Lönnecke, Peter, Crews, Brenda, Marnett, Lawrence J., Pietzsch, Jens, Kniess, Torsten, Hey-Hawkins, Evamarie
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849512/
https://ncbi.nlm.nih.gov/pubmed/23303738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200455
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