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2-Carbaborane-3-phenyl-1H-indoles – Synthesis via McMurry Reaction and COX Inhibition Activity

Cyclooxygenase-2 (COX-2) inhibitors have been in the focus of medicinal chemistry for years and many compounds exhibiting high selectivity and affinity were developed. As carbaboranes represent interesting pharmacophores as phenyl mimetics in drug development, this paper presents the synthesis of ca...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Laube, Markus, Neumann, Wilma, Scholz, Matthias, Lönnecke, Peter, Crews, Brenda, Marnett, Lawrence J., Pietzsch, Jens, Kniess, Torsten, Hey-Hawkins, Evamarie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849512/
https://ncbi.nlm.nih.gov/pubmed/23303738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200455
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