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Synthesis and Evaluation of Carbaborane Derivatives of Indomethacin as Cyclooxygenase Inhibitors

Nonsteroidal anti-inflammatory drugs (NSAIDs) exert their pharmacological activities by inhibiting cyclooxygenase (COX)-1 and COX-2. Previous studies have shown that esters and amides of non-selective inhibitors such as indomethacin are selective against COX-2, which is the therapeutically relevant...

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Bibliografski detalji
Glavni autori: Scholz, Matthias, Blobaum, Anna L., Marnett, Lawrence J., Hey-Hawkins, Evamarie
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401020/
https://ncbi.nlm.nih.gov/pubmed/21524587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.03.054
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