The Rationale for Using Rifabutin in the Treatment of MDR and XDR Tuberculosis Outbreaks

Por Sirgel, Frederick A., Warren, Robin M., Böttger, Erik C., Klopper, Marisa, Victor, Thomas C., van Helden, Paul D.
Publicado em 2013

Moxifloxacin Retains Antimycobacterial Activity in the Presence of gyrA Mutations

Por McGrath, Marieta, Gey van Pittius, Nico C., Sirgel, Frederick A., Van Helden, Paul D., Warren, Robin M.
Publicado em 2014

The pyrazinamide susceptibility breakpoint above which combination therapy fails

Por Gumbo, Tawanda, Chigutsa, Emmanuel, Pasipanodya, Jotam, Visser, Marianne, van Helden, Paul D., Sirgel, Frederick A, McIlleron, Helen
Publicado em 2014

Correction: The Rationale for Using Rifabutin in the Treatment of MDR and XDR Tuberculosis Outbreaks

Por Sirgel, Frederick A., Warren, Robin M., Böttger, Erik C., Klopper, Marisa, Victor, Thomas C., van Helden, Paul D.
Publicado no PLoS One (2015)

Impact of Nonlinear Interactions of Pharmacokinetics and MICs on Sputum Bacillary Kill Rates as a Marker of Sterilizing Effect in Tuberculosis

Por Chigutsa, Emmanuel, Pasipanodya, Jotam G., Visser, Marianne E., van Helden, Paul D., Smith, Peter J., Sirgel, Frederick A., Gumbo, Tawanda, McIlleron, Helen
Publicado no Antimicrob Agents Chemother (2014)

Moxifloxacin Population Pharmacokinetics and Model-Based Comparison of Efficacy between Moxifloxacin and Ofloxacin in African Patients

Por Zvada, Simbarashe P., Denti, Paolo, Sirgel, Frederick A., Chigutsa, Emmanuel, Hatherill, Mark, Charalambous, Salome, Mungofa, Stanley, Wiesner, Lubbe, Simonsson, Ulrika S. H., Jindani, Amina, Harrison, Thomas, McIlleron, Helen M.
Publicado em 2014

Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates

Por Torres, Jessica N, Paul, Lynthia V, Rodwell, Timothy C, Victor, Thomas C, Amallraja, Anu M, Elghraoui, Afif, Goodmanson, Amy P, Ramirez-Busby, Sarah M, Chawla, Ashu, Zadorozhny, Victoria, Streicher, Elizabeth M, Sirgel, Frederick A, Catanzaro, Donald, Rodrigues, Camilla, Gler, Maria Tarcela, Crudu, Valeru, Catanzaro, Antonino, Valafar, Faramarz
Publicado no Emerg Microbes Infect (2015)

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target I...

Por Wilson, Colin R., Gessner, Richard K., Moosa, Atica, Seldon, Ronnett, Warner, Digby F., Mizrahi, Valerie, Soares de Melo, Candice, Simelane, Sandile B., Nchinda, Aloysius, Abay, Efrem, Taylor, Dale, Njoroge, Mathew, Brunschwig, Christel, Lawrence, Nina, Boshoff, Helena I. M., Barry, Clifton E., Sirgel, Frederick A., van Helden, Paul, Harris, C. John, Gordon, Richard, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Boesche, Markus, Drewes, Gerard, Sanz, Olalla, Santos, Gracia, Rebollo-Lopez, Maria José, Urones, Beatriz, Selenski, Carolyn, Lafuente-Monasterio, Maria Jose, Axtman, Matthew, Lelièvre, Joël, Ballell, Lluis, Mueller, Rudolf, Street, Leslie J., Ghorpade, Sandeep R., Chibale, Kelly
Publicado no J Med Chem (2017)