The Rationale for Using Rifabutin in the Treatment of MDR and XDR Tuberculosis Outbreaks

Genetically related Mycobacterium tuberculosis strains with alterations at codon 516 in the rpoB gene were observed amongst a substantial number of patients with drug resistant tuberculosis in the Eastern Cape Province (ECP) of South Africa. Mutations at codon 516 are usually associated with lower l...

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Detalhes bibliográficos
Main Authors: Sirgel, Frederick A., Warren, Robin M., Böttger, Erik C., Klopper, Marisa, Victor, Thomas C., van Helden, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602005/
https://ncbi.nlm.nih.gov/pubmed/23527189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059414
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