The Rationale for Using Rifabutin in the Treatment of MDR and XDR Tuberculosis Outbreaks

Genetically related Mycobacterium tuberculosis strains with alterations at codon 516 in the rpoB gene were observed amongst a substantial number of patients with drug resistant tuberculosis in the Eastern Cape Province (ECP) of South Africa. Mutations at codon 516 are usually associated with lower l...

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Main Authors: Sirgel, Frederick A., Warren, Robin M., Böttger, Erik C., Klopper, Marisa, Victor, Thomas C., van Helden, Paul D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602005/
https://ncbi.nlm.nih.gov/pubmed/23527189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059414
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