Moxifloxacin Retains Antimycobacterial Activity in the Presence of gyrA Mutations

Moxifloxacin-resistant Mycobacterium tuberculosis mutants were selected in vitro using different concentrations of moxifloxacin. gyrA mutations at codons 88 and 94 were associated with resistance (defined as an MIC of ≥2 μg/ml) (P < 0.0001 and P = 0.0053, respectively). Despite the presence of gy...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McGrath, Marieta, Gey van Pittius, Nico C., Sirgel, Frederick A., Van Helden, Paul D., Warren, Robin M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993264/
https://ncbi.nlm.nih.gov/pubmed/24514091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02583-13
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