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Serine-to-Asparagine Substitution in the GyrA Gene Leads to Quinolone Resistance in Moxifloxacin-Exposed Chlamydia pneumoniae

Quinolone resistance of Chlamydia pneumoniae has not been described previously. Serial subcultures of C. pneumoniae under increasing moxifloxacin concentrations (0.0125 to 6.4 mg/liter) resulted in a 256-fold MIC increase compared to moxifloxacin-naive strains. GyrA gene sequencing revealed a novel...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rupp, Jan, Gebert, Andreas, Solbach, Werner, Maass, Matthias
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC538918/
https://ncbi.nlm.nih.gov/pubmed/15616321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.406-407.2005
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