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Moxifloxacin Retains Antimycobacterial Activity in the Presence of gyrA Mutations
Moxifloxacin-resistant Mycobacterium tuberculosis mutants were selected in vitro using different concentrations of moxifloxacin. gyrA mutations at codons 88 and 94 were associated with resistance (defined as an MIC of ≥2 μg/ml) (P < 0.0001 and P = 0.0053, respectively). Despite the presence of gy...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993264/ https://ncbi.nlm.nih.gov/pubmed/24514091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02583-13 |
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