The pyrazinamide susceptibility breakpoint above which combination therapy fails

OBJECTIVES: To identify the pyrazinamide MIC above which standard combination therapy fails. METHODS: MICs of pyrazinamide were determined for Mycobacterium tuberculosis isolates, cultured from 58 patients in a previous randomized clinical trial in Cape Town, South Africa. The MICs were determined u...

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Detalhes bibliográficos
Main Authors: Gumbo, Tawanda, Chigutsa, Emmanuel, Pasipanodya, Jotam, Visser, Marianne, van Helden, Paul D., Sirgel, Frederick A, McIlleron, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130380/
https://ncbi.nlm.nih.gov/pubmed/24821594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku136
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