Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms

Por Sinha, Amit U, Meller, Jaroslaw
Publicado em 2007

iCanPlot: Visual Exploration of High-Throughput Omics Data Using Interactive Canvas Plotting

Por Sinha, Amit U., Armstrong, Scott A.
Publicado em 2012

Dissecting microregulation of a master regulatory network

Por Sinha, Amit U, Kaimal, Vivek, Chen, Jing, Jegga, Anil G
Publicado em 2008

eXframe: reusable framework for storage, analysis and visualization of genomics experiments

Por Sinha Amit U, Merrill Emily, Armstrong Scott A, Clark Tim W, Das Sudeshna
Publicado em 2011-11-01

eXframe: reusable framework for storage, analysis and visualization of genomics experiments

Por Sinha, Amit U, Merrill, Emily, Armstrong, Scott A, Clark, Tim W, Das, Sudeshna
Publicado em 2011

Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains

Por Trowbridge, Jennifer J., Sinha, Amit U., Zhu, Nan, Li, Mingjie, Armstrong, Scott A., Orkin, Stuart H.
Publicado em 2012

The Wnt/β-catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

Por Wang, Yingzi, Krivtsov, Andrei V., Sinha, Amit U., North, Trista E., Goessling, Wolfram, Feng, Zhaohui, Zon, Leonard I., Armstrong, Scott A.
Publicado em 2010

Polycomb repressive complex 2 is required for MLL-AF9 leukemia

Por Neff, Tobias, Sinha, Amit U., Kluk, Michael J., Zhu, Nan, Khattab, Mohamed H., Stein, Lauren, Xie, Huafeng, Orkin, Stuart H., Armstrong, Scott A.
Publicado em 2012

Chromatin modifying enzymes as modulators of reprogramming

Por Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, Ogan. B., Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.
Publicado em 2012

Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

Por Krivtsov, Andrei V., Figueroa, Maria E., Sinha, Amit U., Stubbs, Matthew C., Feng, Zhaohui, Valk, Peter J.M., Delwel, Ruud, Döhner, Konstanze, Bullinger, Lars, Kung, Andrew L., Melnick, Ari M., Armstrong, Scott A.
Publicado no Leukemia (2012)

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

Por Krivtsov, Andrei V., Feng, Zhaohui, Lemieux, Madeleine E., Faber, Joerg, Vempati, Sridhar, Sinha, Amit U., Xia, Xiaobo, Jesneck, Jonathan, Bracken, Adrian P., Silverman, Lewis B., Kutok, Jeffery L., Kung, Andrew L., Armstrong, Scott A.
Publicado em 2008

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l

Por Deshpande, Aniruddha J., Chen, Liying, Fazio, Maurizio, Sinha, Amit U., Bernt, Kathrin M., Banka, Deepti, Dias, Stuart, Chang, Jenny, Olhava, Edward J., Daigle, Scott R., Richon, Victoria M., Pollock, Roy M., Armstrong, Scott A.
Publicado em 2013

MLL-rearranged Leukemia is Dependent on Aberrant H3K79 Methylation by DOT1L

Por Bernt, Kathrin M., Zhu, Nan, Sinha, Amit U., Vempati, Sridhar, Faber, Joerg, Krivtsov, Andrei V., Feng, Zhaohui, Punt, Natalie, Daigle, Amanda, Bullinger, Lars, Pollock, Roy M., Richon, Victoria M., Kung, Andrew L., Armstrong, Scott A.
Publicado em 2011

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia

Por Riedel, Simone S., Haladyna, Jessica N., Bezzant, Matthew, Stevens, Brett, Pollyea, Daniel A., Sinha, Amit U., Armstrong, Scott A., Wei, Qi, Pollock, Roy M., Daigle, Scott R., Jordan, Craig T., Ernst, Patricia, Neff, Tobias, Bernt, Kathrin M.
Publicado no J Clin Invest (2016)

mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis

Por Kalaitzidis, Demetrios, Sykes, Stephen M., Wang, Zhu, Punt, Natalie, Tang, Yuefeng, Ragu, Christine, Sinha, Amit U., Lane, Steven W., Souza, Amanda L., Clish, Clary B., Anastasiou, Dimitrios, Gilliland, D. Gary, Scadden, David T., Guertin, David A., Armstrong, Scott A.
Publicado em 2012

MLL-Rearranged B Lymphoblastic Leukemias Selectively Express the Immunoregulatory Carbohydrate-Binding Protein Galectin-1

Por Juszczynski, Przemyslaw, Rodig, Scott J., Ouyang, Jing, O’Donnell, Evan, Takeyama, Kunihiko, Mlynarski, Wojciech, Mycko, Katarzyna, Szczepanski, Tomasz, Gaworczyk, Anna, Krivtsov, Andrei, Faber, Joerg, Sinha, Amit U., Rabinovich, Gabriel A., Armstrong, Scott A., Kutok, Jeffery L., Shipp, Margaret A.
Publicado em 2010

Mutations in epigenetic regulators including SETD2 are gained during relapse in pediatric acute lymphoblastic leukemia

Por Mar, Brenton G, Bullinger, Lars B, McLean, Kathleen M, Grauman, Peter V, Harris, Marian H, Stevenson, Kristen, Neuberg, Donna S, Sinha, Amit U, Sallan, Stephen E, Silverman, Lewis B, Kung, Andrew L, Nigro, Luca Lo, Ebert, Benjamin L, Armstrong, Scott A
Publicado em 2014

MLL-AF9– and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C

Por Zhu, Nan, Chen, Mo, Eng, Rowena, DeJong, Joshua, Sinha, Amit U., Rahnamay, Noushin F., Koche, Richard, Al-Shahrour, Fatima, Minehart, Janna C., Chen, Chun-Wei, Deshpande, Aniruddha J., Xu, Haiming, Chu, S. Haihua, Ebert, Benjamin L., Roeder, Robert G., Armstrong, Scott A.
Publicado no J Clin Invest (2016)

AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes

Por Deshpande, Aniruddha J., Deshpande, Anagha, Sinha, Amit U., Chen, Liying, Chang, Jenny, Cihan, Ali, Fazio, Maurizio, Chen, Chun-wei, Zhu, Nan, Koche, Richard, Dzhekieva, Liuda, Ibáñez, Gloria, Dias, Stuart, Banka, Deepti, Krivtsov, Andrei, Luo, Minkui, Roeder, Robert G., Bradner, James E., Bernt, Kathrin M., Armstrong, Scott A.
Publicado no Cancer Cell (2014)