Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

MLL-fusion proteins can induce acute myeloid leukemias (AML) from either hematopoietic stem cells (HSC) or granulocyte macrophage progenitors (GMP), but it remains unclear if the cell of origin influences the biology of the resultant leukemia. MLL-AF9 transduced single HSC or GMP could be continuous...

詳細記述

保存先:
書誌詳細
出版年:Leukemia
主要な著者: Krivtsov, Andrei V., Figueroa, Maria E., Sinha, Amit U., Stubbs, Matthew C., Feng, Zhaohui, Valk, Peter J.M., Delwel, Ruud, Döhner, Konstanze, Bullinger, Lars, Kung, Andrew L., Melnick, Ari M., Armstrong, Scott A.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693300/
https://ncbi.nlm.nih.gov/pubmed/23235717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.363
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