EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs

The proto-oncogene EVI1 (ecotropic viral integration site-1), located on chromosome band 3q26, is aberrantly expressed in human acute myeloid leukemia (AML) with 3q26 rearrangements. In the current study, we showed, in a large AML cohort carrying 11q23 translocations, that ∼ 43% of all mixed lineage...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bindels, Eric M. J., Havermans, Marije, Lugthart, Sanne, Erpelinck, Claudia, Wocjtowicz, Elizabeth, Krivtsov, Andrei V., Rombouts, Elwin, Armstrong, Scott A., Taskesen, Erdogan, Haanstra, Jurgen R., Beverloo, H. Berna, Döhner, Hartmut, Hudson, Wendy A., Kersey, John H., Delwel, Ruud, Kumar, Ashish R.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Clinical Trials and Observations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382941/
https://ncbi.nlm.nih.gov/pubmed/22553314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-393827
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki