Single Cell Glucose Uptake Assays: A Cautionary Tale

von Sinclair, Linda V., Barthelemy, Celine, Cantrell, Doreen A.
Veröffentlicht in Immunometabolism (2020)

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

von Marchingo, Julia M, Sinclair, Linda V, Howden, Andrew JM, Cantrell, Doreen A
Veröffentlicht in eLife (2020)

Single cell analysis of kynurenine and System L amino acid transport in T cells

von Sinclair, Linda V., Neyens, Damien, Ramsay, George, Taylor, Peter M., Cantrell, Doreen A.
Veröffentlicht in Nat Commun (2018)

Antigen receptor control of amino acid transport coordinates the metabolic re-programming that is essential for T cell differentiation

von Sinclair, Linda V., Rolf, Julia, Emslie, Elizabeth, Shi, Yun-Bo, Taylor, Peter M., Cantrell, Doreen A.
Veröffentlicht 2013

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs

von Rollings, Christina M., Sinclair, Linda V., Brady, Hugh J. M., Cantrell, Doreen A., Ross, Sarah H.
Veröffentlicht in Sci Signal (2018)

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

von Matthews, Sharon A., Navarro, Maria N., Sinclair, Linda V., Emslie, Elizabeth, Feijoo-Carnero, Carmen, Cantrell, Doreen A.
Veröffentlicht 2010

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

von Navarro, Maria N., Sinclair, Linda V., Feijoo-Carnero, Carmen, Clarke, Rosemary, Matthews, Sharon A., Cantrell, Doreen A.
Veröffentlicht 2012

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

von Finlay, David K., Sinclair, Linda V., Feijoo, Carmen, Waugh, Caryll M., Hagenbeek, Thijs J., Spits, Hergen, Cantrell, Doreen A.
Veröffentlicht 2009

Temporal differences in the dependency on Phosphoinositide Dependent Kinase 1 distinguish the development of iNKT cells and conventional T cells

von Finlay, David K., Kelly, April P., Clarke, Rosemary, Sinclair, Linda V., Deak, Maria, Alessi, Dario R., Cantrell, Doreen A.
Veröffentlicht 2010

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

von Howden, Andrew JM, Hukelmann, Jens L, Brenes, Alejandro, Spinelli, Laura, Sinclair, Linda V, Lamond, Angus I, Cantrell, Doreen A
Veröffentlicht in Nat Immunol (2019)

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

von Swamy, Mahima, Pathak, Shalini, Grzes, Katarzyna M., Damerow, Sebastian, Sinclair, Linda V., van Aalten, Daan M. F., Cantrell, Doreen A.
Veröffentlicht in Nat Immunol (2016)

Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism

von Macintyre, Andrew N., Finlay, David, Preston, Gavin, Sinclair, Linda V., Waugh, Caryll M., Tamas, Peter, Feijoo, Carmen, Okkenhaug, Klaus, Cantrell, Doreen A.
Veröffentlicht 2011

Phosphoinositide 3-kinase (PI3K) and nutrient sensing mTOR (mammalian target of rapamycin) pathways control T lymphocyte trafficking

von Sinclair, Linda V, Finlay, David, Feijoo, Carmen, Cornish, Georgina H, Gray, Alex, Ager, Ann, Okkenhaug, Klaus, Hagenbeek, Thijs J, Spits, Hergen, Cantrell, Doreen A
Veröffentlicht 2008

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8(+) T cells

von Finlay, David K., Rosenzweig, Ella, Sinclair, Linda V., Feijoo-Carnero, Carmen, Hukelmann, Jens L., Rolf, Julia, Panteleyev, Andrey A., Okkenhaug, Klaus, Cantrell, Doreen A.
Veröffentlicht 2012

Glucose represses dendritic cell-induced T cell responses

von Lawless, Simon J., Kedia-Mehta, Nidhi, Walls, Jessica F., McGarrigle, Ryan, Convery, Orla, Sinclair, Linda V., Navarro, Maria N., Murray, James, Finlay, David K.
Veröffentlicht in Nat Commun (2017)

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes

von Preston, Gavin C, Sinclair, Linda V, Kaskar, Aneesa, Hukelmann, Jens L, Navarro, Maria N, Ferrero, Isabel, MacDonald, H Robson, Cowling, Victoria H, Cantrell, Doreen A
Veröffentlicht in EMBO J (2015)

The cytotoxic T cell proteome and its shaping by mammalian Target of Rapamycin

von Hukelmann, Jens L., Anderson, Karen E., Sinclair, Linda V., Grzes, Katarzyna M., Murillo, Alejandro Brenes, Hawkins, Phillip T., Stephens, Len R., Lamond, Angus I., Cantrell, Doreen A.
Veröffentlicht in Nat Immunol (2015)

Exhausted CD4(+) T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression

von Villegas-Mendez, Ana, Khandelwal, Garima, McGowan, Lucy M., Dookie, Rebecca S., Haley, Michael J., George, Charlotte, Sims, David, Lord, Graham M., Sinclair, Linda V., Jenner, Richard G., Couper, Kevin N.
Veröffentlicht in J Immunol (2020)

Antigen receptor control of methionine metabolism in T cells

von Sinclair, Linda V, Howden, Andrew JM, Brenes, Alejandro, Spinelli, Laura, Hukelmann, Jens L, Macintyre, Andrew N, Liu, Xiaojing, Thomson, Sarah, Taylor, Peter M, Rathmell, Jeffrey C, Locasale, Jason W, Lamond, Angus I, Cantrell, Doreen A
Veröffentlicht in eLife (2019)

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

von Loftus, Róisín M., Assmann, Nadine, Kedia-Mehta, Nidhi, O’Brien, Katie L., Garcia, Arianne, Gillespie, Conor, Hukelmann, Jens L., Oefner, Peter J., Lamond, Angus I., Gardiner, Clair M., Dettmer, Katja, Cantrell, Doreen A., Sinclair, Linda V., Finlay, David K.
Veröffentlicht in Nat Commun (2018)