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The cytotoxic T cell proteome and its shaping by mammalian Target of Rapamycin
High-resolution mass spectrometry maps the cytotoxic T lymphocyte (CTL) proteome and the impact of mammalian target of rapamycin complex 1 (mTORC1) on CTLs. The CTL proteome was dominated by metabolic regulators and granzymes and mTORC1 selectively repressed and promoted expression of subset of CTL...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685757/ https://ncbi.nlm.nih.gov/pubmed/26551880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3314 |
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