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Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs
Interleukin-2 (IL-2) and Janus kinases (JAKs) regulate transcriptional programs and protein synthesis to promote the differentiation of effector CD8(+) cytotoxic T cells (CTLs). Using high-resolution mass spectrometry, we generated an in-depth characterization of how IL-2 and JAKs configure the CTL...
Tallennettuna:
| Julkaisussa: | Sci Signal |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483062/ https://ncbi.nlm.nih.gov/pubmed/29666307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aap8112 |
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