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Temporal differences in the dependency on Phosphoinositide Dependent Kinase 1 distinguish the development of iNKT cells and conventional T cells
The present study uses two independent genetic strategies to explore the requirement for Phosphoinositide dependent kinase-1 (PDK1) in the development of mature T cell populations from CD4/CD8 double positive thymocytes. The data show that CD4/CD8 double positive thymocytes that do not express PDK1...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014570/ https://ncbi.nlm.nih.gov/pubmed/20944007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000827 |
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