Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival

Invariant natural killer T (iNKT) cells are innate-like T cells that recognize glycolipid antigens and play critical roles in regulation of immune responses. Based on expression of the transcription factors (TFs) Tbet, Plzf, and Rorγt, iNKT cells have been classified in effector subsets that emerge...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Uddin, Mohammad Nizam, Sultana, Dil Afroz, Lorentsen, Kyle J., Cho, Jonathan J., Kirst, Mariana E., Brantly, Mark L., Califano, Danielle, Sant'Angelo, Derek B., Avram, Dorina
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941433/
https://ncbi.nlm.nih.gov/pubmed/27330109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521846113
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