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Histone deacetylase 3 is required for iNKT cell development
NKT cells are a distinct subset that have developmental requirements that often differ from conventional T cells. Here, we show that NKT-specific deletion of Hdac3 results in a severe reduction in the number of iNKT cells, particularly of NKT1 cells. In addition, there is decreased cytokine producti...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517478/ https://ncbi.nlm.nih.gov/pubmed/28724935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06102-5 |
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