The transcriptional repressor NKAP is required for the development of iNKT cells

Invariant natural killer T cells have a distinct developmental pathway from conventional αβ T cells. Here we demonstrate that the transcriptional repressor NKAP is required for invariant natural killer T cell but not conventional T cell development. In CD4-cre NKAP conditional knockout mice, invaria...

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Hlavní autoři: Thapa, Puspa, Das, Joy, McWilliams, Douglas, Shapiro, Michael, Sundsbak, Rhianna, Nelson-Holte, Molly, Tangen, Sarah, Anderson, Joshua, Desiderio, Stephen, Hiebert, Scott, Sant’Angelo, Derek B., Shapiro, Virginia Smith
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615467/
https://ncbi.nlm.nih.gov/pubmed/23481390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2580
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